Evidence map›Paper›PMID 37679795›Full record

ArticleAnnals of clinical microbiology and antimicrobials2023

Emergence of carbapenem-resistant enterobacterales co-harboring bla

Bhaskar Jyoti Das, K Melson Singha, Jayalaxmi Wangkheimayum, Debadatta Dhar Chanda, Amitabha Bhattacharjee

Abstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bhaskar Jyoti DasDepartment of Microbiology, Assam University, Silchar, Dist : Cachar, 788011, Assam, India.
K Melson SinghaDepartment of Microbiology, Silchar Medical College and Hospital, Silchar, Dist : Cachar, Assam, PIN : 788014, India.
Jayalaxmi WangkheimayumDepartment of Microbiology, Assam University, Silchar, Dist : Cachar, 788011, Assam, India.
Debadatta Dhar ChandaDepartment of Microbiology, Silchar Medical College and Hospital, Silchar, Dist : Cachar, Assam, PIN : 788014, India.
Amitabha BhattacharjeeDepartment of Microbiology, Assam University, Silchar, Dist : Cachar, 788011, Assam, India. ab0404@gmail.com.

Funding

Department of Biotechnology (DBT), Government of India DBT-NER Twinning BT/PR242/NER/95/716/2017 dated 28.09.2018Indian Council of Medical Research ICMR-SRF 2020-7955/CMB-BMS dated 09.03.2021
6 · The paper itself

Abstract

backgroundCarbapenem-Resistant Enterobacterales (CRE) has been categorized as pathogens of critical priority by World Health organization (WHO) as they pose significant threat to global public health. Carbapenemase production considered as the principal resistance mechanism against carbapenems and with the recent surge and expansion of carbapenemases and its variants among clinically significant bacteria in India, the present study reports expansion bla

methodsBacterial isolates were collected from a tertiary referral hospital and identified through VITEK® 2 Compact automated System (Biomerieux, France). Rapidec® Carba NP (Biomerieux, France) was used to investigate carbapenemase production followed by antibiotic susceptibility testing through Kirby-Bauer Disc Diffusion method and agar dilution method. Class D carbapenemase genes were targeted through PCR assay followed by investigation of horizontal transmission of bla

resultsThe carbapenem-resistant Escherichia coli (BJD_EC456) and Serratia marcescens (BJD_SM81) received during the study from the tertiary referral hospital were isolated from sputum and blood samples respectively. PCR assay followed by whole genome sequencing revealed that the isolates co-harbor bla

conclusionsThe study provides a local epidemiological information regarding carbapenem resistance aided by transposon and insertion sequences associated bla

Indexed as

CarbapenemsDNA Transposable ElementsAminoglycosidesAnti-Bacterial AgentsEscherichia coliHumansIndiaAminoglycosidesAnti-Bacterial AgentsCarbapenemsDNA Transposable ElementsAntimicrobial resistancebla OXA−58bla OXA−78Carbapenem-resistant EnterobacteralesISAba26Tn6080

Identifiers

PMID37679795
PMCPMC10486080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.