Evidence map›Paper›PMID 37679657›Full record

ArticleInternational journal of computer assisted radiology and surgery2024

A simulation-based phantom model for generating synthetic mitral valve image data-application to MRI acquisition planning.

Chiara Manini, Olena Nemchyna, Serdar Akansel, Lars Walczak, Lennart Tautz, Christoph Kolbitsch, Volkmar Falk, Simon Sündermann, Titus Kühne, Jeanette Schulz-Menger and 1 more

Abstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chiara ManiniInstitute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany. chiara.manini@dhzc-charite.de.ORCID http://orcid.org/0000-0001-5357-3396
Olena NemchynaDepartment of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany.ORCID http://orcid.org/0000-0002-0564-533X
Serdar AkanselDepartment of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany.ORCID http://orcid.org/0000-0002-3479-4537
Lars WalczakInstitute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany.ORCID http://orcid.org/0000-0001-6124-0671
Lennart TautzFraunhofer MEVIS, Berlin, Germany.ORCID http://orcid.org/0000-0002-1758-6111
Christoph KolbitschPhysikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany.ORCID http://orcid.org/0000-0002-4355-8368
Volkmar FalkCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-7911-8620
Simon SündermannCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-4927-1584
Titus KühneInstitute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany.ORCID http://orcid.org/0000-0003-1631-4824
Jeanette Schulz-MengerCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-3100-1092
Anja HennemuthInstitute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany.ORCID http://orcid.org/0000-0002-0737-7375

Funding

Bundesministerium für Bildung und Forschung 16SV8649Deutsche Forschungsgemeinschaft BIOQICDeutsche Forschungsgemeinschaft GRK2260
6 · The paper itself

Abstract

purposeNumerical phantom methods are widely used in the development of medical imaging methods. They enable quantitative evaluation and direct comparison with controlled and known ground truth information. Cardiac magnetic resonance has the potential for a comprehensive evaluation of the mitral valve (MV). The goal of this work is the development of a numerical simulation framework that supports the investigation of MRI imaging strategies for the mitral valve.

methodsWe present a pipeline for synthetic image generation based on the combination of individual anatomical 3D models with a position-based dynamics simulation of the mitral valve closure. The corresponding images are generated using modality-specific intensity models and spatiotemporal sampling concepts. We test the applicability in the context of MRI imaging strategies for the assessment of the mitral valve. Synthetic images are generated with different strategies regarding image orientation (SAX and rLAX) and spatial sampling density.

resultsThe suitability of the imaging strategy is evaluated by comparing MV segmentations against ground truth annotations. The generated synthetic images were compared to ones acquired with similar parameters, and the result is promising. The quantitative analysis of annotation results suggests that the rLAX sampling strategy is preferable for MV assessment, reaching accuracy values that are comparable to or even outperform literature values.

conclusionThe proposed approach provides a valuable tool for the evaluation and optimization of cardiac valve image acquisition. Its application to the use case identifies the radial image sampling strategy as the most suitable for MV assessment through MRI.

Indexed as

Mitral ValveMitral Valve InsufficiencyComputer SimulationHumansMagnetic Resonance ImagingPhantoms, ImagingCardiac phantomImage simulationMagnetic resonance imagingMitral valveModelingSegmentation

Identifiers

PMID37679657
PMCPMC10881710

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.