Evidence map›Paper›PMID 37679618›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Isolation and Characterization of Single-Domain Antibodies from Immune Phage Display Libraries.

Martin A Rossotti, Frederic Trempe, Henk van Faassen, Greg Hussack, Mehdi Arbabi-Ghahroudi

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Martin A RossottiHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Frederic TrempeHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Henk van FaassenHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Greg HussackHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Mehdi Arbabi-GhahroudiHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada. mehdi.arbabi@nrc-cnrc.gc.ca.
National Research Council Canada · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naturally occurring heavy chain antibodies (HCAbs) in Camelidae species were a surprise discovery in 1993 by Hamers et al. Since that time, antibody fragments derived from HCAbs have garnered considerable attention by researchers and biotechnology companies. Due to their biophysico-chemical advantages over conventional antibody fragments, camelid single-domain antibodies (sdAbs, V

Indexed as

Arthritis, RheumatoidBacteriophagesBlood Group AntigensCamelids, New WorldSingle-Domain AntibodiesAnimalsAntibodies, MonoclonalBiotechnologyCamelidaeFactor VAntibodies, MonoclonalBlood Group AntigensFactor VSingle-Domain AntibodiesCamelidFlow cytometryLibrary constructionPanningPhage displaySingle-domain antibodySite-specific biotinylationSurface plasmon resonanceVHH

Identifiers

PMID37679618
OpenAlexW4386494376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.