ArticleLeukemia2023
Secondary-type mutations do not impact outcome in NPM1-mutated acute myeloid leukemia - implications for the European LeukemiaNet risk classification.
Open access · hybridAbstract read
In one paragraph
Article in Leukemia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
10.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Prognostic implications of myelodysplasia-related gene mutations inHaematologica · 2026Pooled it
- Impact of secondary-type mutations on the prognosis of AML patients with NPM1 mutation: a systematic review and meta-analysis.Annals of hematology · 2025Pooled it
- Prognostic impact of myelodysplasia-related gene mutations in ELN-2022 favorable-risk acute myeloid leukemia subtypes.Annals of medicine · 2026Article
- Prognostic impact of age and MDS-associated mutations inBlood neoplasia · 2026Article
- Acute Myeloid Leukemia Subtype-Specific Prognostic Value of NGS in the Setting of Intensive Chemotherapy.American journal of hematology · 2026Article
- Prognostic Significance of Secondary-Type Mutations in NPM1-Mutated Acute Myeloid Leukemia.Cancer medicine · 2026Article
- Acute Myeloid Leukemia with Myelodysplasia-Related Gene Mutations.Journal of clinical medicine · 2026Review
- Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemia.Leukemia · 2026Article
- NPM1c⁺-driven lncRNA dysregulation in AML: Mechanisms, Controversies and translational roadblocks.Translational oncology · 2026Review
- Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia - a HARMONY study.Leukemia · 2026Article
- Prognostic heterogeneity in ASXL1-mutated AML and refinement by an immunophenotype-based score.Frontiers in oncology · 2026Article
- AML, Myelodysplasia-Related: Beyond Classification-Toward Precision Decision-Making.Mediterranean journal of hematology and infectious diseases · 2026Review
- Differential prognostic impact of myelodysplasia-related gene mutations in a European cohort of 4978 intensively treated AML patients.Leukemia · 2026Article
- Multimodal and Data-Driven Assessment of Myeloid Neoplasms Refines Classification across Disease States.Blood cancer discovery · 2025Article
- Prognostic covariates associated with outcomes in patients with NPM1-mutated acute myeloid leukemia.The oncologist · 2025Article
- Effect of NPM1 Mutation Subtype and Co-Mutation Patterns on the Outcomes of Acute Myeloid Leukemia.European journal of haematology · 2025Article
- Prognostic impact of clonal representation of myelodysplasia-related gene mutations in acute myeloid leukemia.Leukemia · 2025Article
- Review
- Acute Myeloid Leukemia: 2025 Update on Diagnosis, Risk-Stratification, and Management.American journal of hematology · 2025Review
- Clinico-Genomic Interrogation of Secondary-Type Acute Myeloid Leukemia: Response and Outcomes to Contemporary Therapies.American journal of hematology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors at 19 institutions in 1 country.
Jan-Niklas Eckardt *Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.ORCID 0000-0002-3649-2823
Marius Bill *Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Christian RauschLaboratory for Leukemia Diagnostics, Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-7364-5526
Klaus MetzelerMedical Clinic and Policlinic I Hematology and Cell Therapy, University Hospital, Leipzig, Germany.ORCID 0000-0003-3920-7490
Karsten SpiekermannLaboratory for Leukemia Diagnostics, Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-5139-4957
Sebastian StasikDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.ORCID 0000-0003-0271-4894
Tim SauerGerman Cancer Research Center (DKFZ) and Medical Clinic V, University Hospital Heidelberg, Heidelberg, Germany.
Sebastian SchollKlinik für Innere Medizin II, Jena University Hospital, Jena, Germany.
Andreas HochhausKlinik für Innere Medizin II, Jena University Hospital, Jena, Germany.
Martina CrysandtDepartment of Hematology, Oncology, Hemostaseology, and Cell Therapy, University Hospital RWTH Aachen, Aachen, Germany.
Tim H BrümmendorfDepartment of Hematology, Oncology, Hemostaseology, and Cell Therapy, University Hospital RWTH Aachen, Aachen, Germany.
Utz KrugDepartment of Medicine III, Hospital Leverkusen, Leverkusen, Germany.
Bernhard WörmannDepartment of Hematology, Oncology and Tumor Immunology, Charité, Berlin, Germany.ORCID 0000-0003-2273-5502
Wolfgang HiddemannLaboratory for Leukemia Diagnostics, Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.
Dennis GörlichInstitute for Biostatistics and Clinical Research, University Muenster, Muenster, Germany.ORCID 0000-0002-2574-9419
Cristina SauerlandInstitute for Biostatistics and Clinical Research, University Muenster, Muenster, Germany.
Björn SteffenMedical Clinic II, University Hospital Frankfurt, Frankfurt (Main), Germany.ORCID 0009-0002-6693-4079
Hermann EinseleMedical Clinic and Policlinic II, University Hospital Würzburg, Würzburg, Germany.
Andreas NeubauerDepartment of Hematology, Oncology and Immunology, Philipps-University-Marburg, Marburg, Germany.
Andreas BurchertDepartment of Hematology, Oncology and Immunology, Philipps-University-Marburg, Marburg, Germany.ORCID 0000-0002-8411-8844
Kerstin Schäfer-EckartDepartment of Internal Medicine V, Paracelsus Medizinische Privatuniversität and University Hospital Nuremberg, Nuremberg, Germany.
Wolfgang E BerdelDepartment of Medicine A, University Hospital Münster, Münster, Germany.ORCID 0000-0002-3030-6567
Christoph SchliemannDepartment of Medicine A, University Hospital Münster, Münster, Germany.ORCID 0000-0003-1755-9583
Stefan W KrauseUniversity Hospital Erlangen, Erlangen,, Germany.ORCID 0000-0002-5259-4651
Mathias HänelMedical Clinic III, Chemnitz Hospital AG, Chemnitz, Germany.
Maher HanounDepartment of Hematology, University Hospital Essen, Essen, Germany.ORCID 0000-0002-1754-8940
Martin KaufmannDepartment of Hematology, Oncology and Palliative Care, Robert-Bosch-Hospital, Stuttgart, Germany.
Lars FranseckyDepartment of Internal Medicine, University Hospital Kiel, Kiel, Germany.
Jan BraessHospital Barmherzige Brueder Regensburg, Regensburg, Germany.
Leo RuhnkeDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Johannes ScheteligDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.ORCID 0000-0002-2780-2981
Jan Moritz MiddekeDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Hubert ServeMedical Clinic II, University Hospital Frankfurt, Frankfurt (Main), Germany.
Claudia D BaldusDepartment of Internal Medicine, University Hospital Kiel, Kiel, Germany.ORCID 0000-0002-0748-834X
Uwe PlatzbeckerMedical Clinic and Policlinic I Hematology and Cell Therapy, University Hospital, Leipzig, Germany.ORCID 0000-0003-1863-3239
Carsten Müller-TidowGerman Cancer Research Center (DKFZ) and Medical Clinic V, University Hospital Heidelberg, Heidelberg, Germany.
Martin BornhäuserDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Tobias HeroldLaboratory for Leukemia Diagnostics, Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-9615-9432
Christian ThiedeDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.ORCID 0000-0003-1241-2048
Christoph RölligDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany. Christoph.Roellig@ukdd.de.
University Hospital Carl Gustav Carus · DELudwig-Maximilians-Universität München · DEGerman Cancer Research Center · DEGerman Cancer Society · DEGoethe University Frankfurt · DEJena University Hospital · DEPhilipps University of Marburg · DERWTH Aachen University · DEUniversity Hospital Leipzig · DEUniversity Hospital Münster · DECharité - Universitätsmedizin Berlin · DEEssen University Hospital · DEKlinikum Chemnitz · DEKlinikum Leverkusen · DEKrankenhaus Barmherzige Brüder · DEParacelsus Medizinische Privatuniversität · DERobert Bosch Hospital · DEUniversitätsklinikum Erlangen · DEUniversitätsklinikum Würzburg · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Leukemia, Myeloid, AcuteHumansMutationNuclear ProteinsPrognosisNuclear Proteins
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.