Evidence map›Paper›PMID 37679048›Full record

ArticleNeurology2023

Mortality and Causes of Death in Children With Cerebral Palsy With Scoliosis Treated With and Without Surgery.

Matti Ahonen, Ilkka Helenius, Mika Gissler, Ira Jeglinsky-Kankainen

Erratum issued Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06934278 (Pooled Human Plasma vs Crystalloid in The Management of Children Undergoing Instrumented Spinal Fusion for Scoliosis), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06934278 phase3recruitingnot on this mapstarted 2025, after this paper: background citation

Pooled Human Plasma vs Crystalloid in The Management of Children Undergoing Instrumented Spinal Fusion for Scoliosis: A Double-Blind, Randomized Clinical Trial

TypeinterventionalSponsorTurku University HospitalRan2025 to 2030Enrolled194ConditionsAdolescent Idiopathic Scoliosis (AIS), Neuromuscular ScoliosisArmsPooled human plasma, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Article
  5. What's new in the pediatric spine?Journal of children's orthopaedics · 2025
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matti AhonenFrom the Helsinki University Hospital (M.A.); Department of Orthopaedics and Traumatology (I.H.), University of Helsinki and Helsinki University Hospital; THL Finnish Institute for Health and Welfare (M.G.); and Department of Health and Welfare (I.J.-K.), Arcada University of Applied Sciences, Helsinki, Finland. matti.ahonen@hus.fi.ORCID 0000-0002-0330-5032
Ilkka HeleniusFrom the Helsinki University Hospital (M.A.); Department of Orthopaedics and Traumatology (I.H.), University of Helsinki and Helsinki University Hospital; THL Finnish Institute for Health and Welfare (M.G.); and Department of Health and Welfare (I.J.-K.), Arcada University of Applied Sciences, Helsinki, Finland.
Mika GisslerFrom the Helsinki University Hospital (M.A.); Department of Orthopaedics and Traumatology (I.H.), University of Helsinki and Helsinki University Hospital; THL Finnish Institute for Health and Welfare (M.G.); and Department of Health and Welfare (I.J.-K.), Arcada University of Applied Sciences, Helsinki, Finland.ORCID 0000-0001-8254-7525
Ira Jeglinsky-KankainenFrom the Helsinki University Hospital (M.A.); Department of Orthopaedics and Traumatology (I.H.), University of Helsinki and Helsinki University Hospital; THL Finnish Institute for Health and Welfare (M.G.); and Department of Health and Welfare (I.J.-K.), Arcada University of Applied Sciences, Helsinki, Finland.
Finnish Institute for Health and Welfare · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo compare mortality and causes of death in scoliotic children with cerebral palsy (CP) with and without scoliosis surgery.

methodsNational population-based registries were searched for children with CP and scoliosis with and without surgery for scoliosis and were analyzed for comorbidities, mortality, and causes of death.

resultsTwo hundred thirty-six had not been operated and 238 had been operated on for scoliosis during the median follow-up of 17.8 (interquartile range [IQR] 11.7-25.7) and 23.0 (IQR 18.4-28.2) years, respectively. Both groups had similar comorbidities. During the follow-up, mortality was higher in the nonsurgically treated group than in the surgically treated group (n = 38/236, 16% and 8.7 per 1,000 follow-up years vs n = 29/238, 12% and 5.3 per 1,000 follow-up years, DISCUSSION: Surgical treatment of scoliosis associates to reduced mortality because of respiratory causes in children with CP and scoliosis. CLASSIFICATION OF EVIDENCE: This study provides Class IV evidence of the effects of spinal fusion on mortality of children with severe scoliosis due to CP.

Indexed as

Cerebral PalsyScoliosisSpinal FusionCausalityCause of DeathChildHumansRetrospective StudiesTreatment Outcome

Identifiers

PMID37679048
PMCPMC10634643
OpenAlexW4386494389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.