Evidence map›Paper›PMID 37678507›Full record

ArticleJournal of sport and health science2024

Elevated brain temperature under severe heat exposure impairs cortical motor activity and executive function.

Xiang Ren Tan, Mary C Stephenson, Sharifah Badriyah Alhadad, Kelvin W Z Loh, Tuck Wah Soong, Jason K W Lee, Ivan C C Low

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Journal of sport and health science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06542419 nacompletednot on this map

The Effect of Selective Brain Cooling on Electrophysiological and Neuroinflammatory Biomarkers of Cognition and Mood

TypeinterventionalSponsorPenn State UniversityRan2024 to 2025Enrolled24ConditionsMental Health, Neurological HealthArmsBrain Cooling
NCT07303933 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Association Between Head Cooling and Cognition, Neuroinflammatory Cytokines, Menstrual Cycle, Sleep Patterns, Mental Health and Concussions

TypeinterventionalSponsorPenn State UniversityRan2026 to 2027Enrolled32ConditionsConcussion (Diagnosis), Concussion Post Syndrome, Concussion, MildArmsBrain Cooling
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Cerebrovascular regulation during heat stress.Experimental physiology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiang Ren TanHealth and Social Sciences, Singapore Institute of Technology, Singapore 138683, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Mary C StephensonCentre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117549, Singapore.
Sharifah Badriyah AlhadadHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore.
Kelvin W Z LohDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore.
Tuck Wah SoongDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore.
Jason K W LeeHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore; Heat Resilience and Performance Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117510, Singapore; N.1 Institute for Health, National University of Singapore, Singapore 117456, Singapore; Campus for Research Excellence and Technological Enterprise (CREATE), Singapore 138602, Singapore. Electronic address: phsjlkw@nus.edu.sg.
Ivan C C LowHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore. Electronic address: phsilcc@nus.edu.sg.
National University of Singapore · SGSingapore-HUJ Alliance for Research and Enterprise · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcessive heat exposure can lead to hyperthermia in humans, which impairs physical performance and disrupts cognitive function. While heat is a known physiological stressor, it is unclear how severe heat stress affects brain physiology and function.

methodsEleven healthy participants were subjected to heat stress from prolonged exercise or warm water immersion until their rectal temperatures (T

resultsT

conclusionSevere heat exposure elevates T

Indexed as

Body TemperatureHeat Stress DisordersBrainExecutive FunctionExerciseFeverHumansIceTemperatureIceBrain functional activityCognitionHeat stressHyperthermiaMotor function

Identifiers

PMID37678507
PMCPMC10980903
OpenAlexW4386531236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.