Evidence map›Paper›PMID 37677073›Full record

Observational studyJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2024

Continuous positive airway pressure treatment improves bone mineral density in men affected by severe obstructive sleep apnea syndrome.

Matteo Carpi, Alberto Cordella, Fabio Placidi, Francesca Izzi, Eleonora Piccirilli, Nicola Biagio Mercuri, Umberto Tarantino, Claudio Liguori

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Bone mineral density: another benefit of continuous positive airway pressure?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Matteo CarpiSleep Medicine Centre, Neurology Unit, University Hospital of Rome "Tor Vergata," Rome, Italy.
Alberto CordellaNeurocenter of Southern Switzerland, Lugano, Switzerland.
Fabio PlacidiSleep Medicine Centre, Neurology Unit, University Hospital of Rome "Tor Vergata," Rome, Italy.
Francesca IzziSleep Medicine Centre, Neurology Unit, University Hospital of Rome "Tor Vergata," Rome, Italy.
Eleonora PiccirilliDepartment of Orthopedics and Traumatology, University Hospital of Rome "Tor Vergata," Rome, Italy.
Nicola Biagio MercuriSleep Medicine Centre, Neurology Unit, University Hospital of Rome "Tor Vergata," Rome, Italy.
Umberto TarantinoDepartment of Orthopedics and Traumatology, University Hospital of Rome "Tor Vergata," Rome, Italy.
Claudio LiguoriSleep Medicine Centre, Neurology Unit, University Hospital of Rome "Tor Vergata," Rome, Italy.
University of Rome Tor Vergata · ITLaboratory for Biomedical Neurosciences · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesObstructive sleep apnea (OSA) and low bone mineral density (BMD) are 2 prevalent conditions with a significant negative impact on patients' well-being and quality of life. Recent research has shown low BMD at different bone sites in male patients with OSA. Although the efficacy of continuous positive airway pressure (CPAP) treatment for OSA has been widely demonstrated, the evidence for understanding its impact on BMD and other bone-related outcomes is insufficient. The aim of this observational study was to investigate the effect of 12 months of CPAP treatment on lumbar and femur BMD and bone-related serum biomarkers in male patients with severe OSA.

methodsSixty patients (mean age: 55.1 ± 9.9 years) were consecutively included and underwent BMD measurement with dual-energy x-ray absorptiometry at baseline and after 12 months of CPAP treatment. Vitamin D, parathyroid hormone, and calcium serum levels were examined at the same time points.

resultsA significant increase in BMD in the L1 (

conclusionsOverall, these findings showed that beneficial OSA treatment might restore bone health and support CPAP treatment as a feasible strategy to improve BMD in male patients with severe OSA. Accordingly, diagnosing and targeting OSA may be warranted in the treatment of male patients with undetermined osteopenia and osteoporosis. CITATION: Carpi M, Cordella A, Placidi F, et al. Continuous positive airway pressure treatment improves bone mineral density in men affected by severe obstructive sleep apnea syndrome.

Indexed as

Bone DensitySleep Apnea, ObstructiveAgedCalciumContinuous Positive Airway PressureHumansMaleMiddle AgedParathyroid HormoneQuality of LifeSyndromeVitamin DCalciumParathyroid HormoneVitamin Dbone mineral densityhypoxiaobstructive sleep apneaosteoporosisvitamin D

Identifiers

PMID37677073
PMCPMC10758556
OpenAlexW4386494186

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.