Evidence map›Paper›PMID 37677026›Full record

Observational studyAnnals of medicine2023

Neuromuscular adaptations after osseointegration of a bone-anchored prosthesis in a unilateral transfemoral amputee - a case study.

Thomas Krauskopf, Torben Lauck, Britta Meyer, Lukas Klein, Marc Mueller, Johanna Kubosch, Georg Herget, Vinzenz von Tscharner, Jennifer Ernst, Thomas Stieglitz and 1 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Thomas KrauskopfLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
Torben LauckLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
Britta MeyerLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
Lukas KleinDepartment of Orthopaedics and Trauma Surgery, Medical Center, University of Freiburg, Freiburg, Germany.
Marc MuellerSanitätshaus Pfänder, Freiburg, Germany.
Johanna KuboschDepartment of Orthopaedics and Trauma Surgery, Medical Center, University of Freiburg, Freiburg, Germany.
Georg HergetDepartment of Orthopaedics and Trauma Surgery, Medical Center, University of Freiburg, Freiburg, Germany.
Vinzenz von TscharnerHuman Performance Laboratory, University of Calgary, Calgary, Canada.
Jennifer ErnstDepartment of Trauma Surgery, Hannover Medical School, Hannover, Germany.
Thomas StieglitzLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
Cristian PasluostaLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
University of Freiburg · DEBernstein Center for Computational Neuroscience Freiburg · DEUniversity Medical Center Freiburg · DEUniversity of Calgary · CAUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany individuals with a lower limb amputation experience problems with the fitting of the socket of their prosthesis, leading to dissatisfaction or device rejection. Osseointegration (OI)- the implantation of a shaft directly interfacing with the remaining bone- is an alternative for these patients. In this observational study, we investigated how bone anchoring influences neuromuscular parameters during balance control in a patient with a unilateral transfemoral amputation. MATERIAL AND

methodsCenter of pressure (CoP) and electromyography (EMG) signals from muscles controlling the hip and the ankle of the intact leg were recorded during quiet standing six months before and one and a half years after this patient underwent an OI surgery. Results were compared to a control group of nine able-bodied individuals.

resultsMuscle co-activation and EMG intensity decreased after bone anchoring, approaching the levels of able-bodied individuals. Muscle co-activation controlling the ankle decreased in the high-frequency range, and the EMG intensity spectrum decreased in the lower-frequency range for all muscles when vision was allowed. With eyes closed, the ankle extensor muscle showed an increased EMG intensity in the high-frequency range post-surgery. CoP length increased in the mediolateral direction of the amputated leg.

conclusionsThese findings point to shifts in the patient's neuromuscular profile towards the one of able-bodied individuals.

Indexed as

AmputeesBone-Anchored ProsthesisElectromyographyHumansMuscle, SkeletalOsseointegrationAmputeebalancebone anchoringneuromuscular controlosseointegration

Identifiers

PMID37677026
PMCPMC10486294
OpenAlexW4386524432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.