ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Profiles of lifestyle health behaviors and cognitive decline in older adults.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of Wearable Technology for Measuring and Characterizing Sedentary Behavior in People With Mild Cognitive Impairment and Dementia: Systematic Review.JMIR aging · 2026Pooled it
- Cerebral amyloid angiopathy, brain iron concentrations, and cognitive decline in older people.Acta neuropathologica · 2026Article
- Positive change in lifestyle behaviors improve cognitive health in older adults: a 10-year cohort study.Archives of public health = Archives belges de sante publique · 2026Article
- Impact of modifiable lifestyle factors on dementia subtypes and brain structural changes across KDIGO risk categories in the UK biobank.Brain imaging and behavior · 2026Article
- Social connection and cognitive health: A review of concepts, measures, and research priorities.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- The Relationship Between the Level of Satisfaction of Maslow's Hierarchy of Needs and Loneliness, Happiness and Life Satisfaction in Elderly Individuals.Journal of clinical nursing · 2026Article
- Causal machine learning analysis identifies subpopulations most likely to benefit from healthy lifestyles for cognitive outcomes.General psychiatry · 2026Article
- A physically and mentally active lifestyle relates to younger brain and cognitive age.GeroScience · 2026Article
- Differential Effects of Lifestyle Indicators on Cognitive Functioning Across Healthy, Dementia, Parkinson's Disease, and Stroke Groups.Journal of clinical medicine · 2026Article
- Physical behaviour profiles and their associations with fitness and function in older adults: a cross-sectional latent profile analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- A Proactive Health Behavior Framework for Cognitive Impairment in Chinese Older Adults: Based on a Four-Factor and Logistic Regression Analysis.Healthcare (Basel, Switzerland) · 2026Article
- Symptom burden, healthcare utilization, and risky behaviors in survivors of the childhood cancer survivor study (CCSS): an observation cohort study.EClinicalMedicine · 2025Article
- How Healthy and Unhealthy Lifestyle Behaviors Affect Cognitive Function-Evidence From Older Adults in Chinese Communities: Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Discussing the Interplay of Social Determinants of Health, Aging, and Alzheimer's Biomarkers in U.S. Latinos.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Review
- Intrinsic factors associated with engagement in healthy lifestyle behaviors for dementia risk reduction in midlife.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- History of chronic pain and opioid use is associated with cognitive decline and mild cognitive impairment.Journal of the International Neuropsychological Society : JINS · 2025Article
- Cognitive function differs across healthy lifestyle behavior profiles: a 10-year population-based prospective cohort study.The journal of nutrition, health & aging · 2025Article
- Exploring influencing factors of healthy lifestyles in rural area among older adults with diabetes based on socioecological model.Scientific reports · 2025Article
- Socioeconomic Disparities in Cognitive Impairment: The Role of Neighborhood Social Cohesion.Innovation in aging · 2025Article
- Structural assessment of family and educational influences on student health behaviours: Insights from a public health perspective.PloS one · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
introductionWe aimed to identify profiles of modifiable, late-life lifestyle health behaviors related to subsequent maintenance of cognition and explore sociodemographics and health characteristics as effect modifiers.
methodsAnalyses used data from 715 older adults without baseline dementia from the Rush Memory and Aging Project and with lifestyle health behaviors (physical activity, cognitive activity, healthy diet, social activity) at baseline and ≥ 2 annual assessments of cognition. We used latent profile analysis to group participants based on behavior patterns and assessed change in cognition by group.
resultsThree latent profiles were identified: high (n = 183), moderate (n = 441), and low (n = 91) engagement in health behaviors. Compared to high engagement, the moderate (mean difference [MD] = -0.02, 95% CI = [-0.03;-0.0002], p = 0.048) and low (MD = -0.06, 95% CI = [-0.08;-0.03], p < 0.0001) groups had faster annual rates of decline in global cognition, with no significant effects modifiers (vascular risk factors, apolipoprotein E [APOE] ε4, motor function). DISCUSSION: Avoiding low levels of lifestyle health behaviors may help maintain cognition. HIGHLIGHTS: Latent profile analysis (LPA) captures lifestyle health behaviors associated with cognitive function. Such behavior include physical activity, cognitive activity, healthy diet, social activity. We used LPA to examine associations of behaviors and cognitive function over time. Older adults with low lifestyle health behaviors showed more rapid decline. To a lesser degree, so did those with moderate lifestyle health behaviors. Vascular conditions and risks, APOEε4, or motor function did not modify the effect.
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