Evidence map›Paper›PMID 37676845›Full record

ArticlePLOS global public health2023

Health systems performance for hypertension control using a cascade of care approach in South Africa, 2011-2017.

Mariet Benade, Zandile Mchiza, Rafeya V Raquib, Sridevi K Prasad, Lily D Yan, Alana T Brennan, Justine Davies, Nikkil Sudharsanan, Jennifer Manne-Goehler, Matthew P Fox and 3 more

Abstract read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mariet BenadeDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0001-9498-3199
Zandile MchizaNon-Communicable Disease Research Unit, South African Medical Research Council, Cape Town, South Africa.
Rafeya V RaquibDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Sridevi K PrasadDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0003-0457-9534
Lily D YanDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States of America.
Alana T BrennanDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Justine DaviesDepartment of Global Health, University of Birmingham, Birmingham, United Kingdom.ORCID https://orcid.org/0000-0001-6834-1838
Nikkil SudharsananHeidelberg Institute for Global Health, Heidelberg University, Heidelberg, Germany.
Jennifer Manne-GoehlerDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA, United States of America.
Matthew P FoxDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Jacob BorDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Sydney B RosenDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Andrew C StokesDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-8502-3636

Funding

Evidence of the burden of diabetes, gaps in the diabetes cascade-of-care and the impact of care and treatment on diabetes outcomes in HIV-positive and HIV-negative patients in South AfricaK01DK116929 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BRENNAN, ALANA TERESA · 2019 to 2023
$866k
NIDDK NIH HHS K01 DK116929
6 · The paper itself

Abstract

Hypertension is a major contributor to global morbidity and mortality. In South Africa, the government has employed a whole systems approach to address the growing burden of non-communicable diseases. We used a novel incident care cascade approach to measure changes in the South African health system's ability to manage hypertension between 2011 and 2017. We used data from Waves 1-5 of the National Income Dynamics Study (NIDS) to estimate trends in the hypertension care cascade and unmet treatment need across four successive cohorts with incident hypertension. We used a negative binomial regression to identify factors that may predict higher rates of hypertension control, controlling for socio-demographic and healthcare factors. In 2011, 19.6% (95%CI 14.2, 26.2) of individuals with incident hypertension were diagnosed, 15.4% (95%CI 10.8, 21.4) were on treatment and 7.1% had controlled blood pressure. By 2017, the proportion of individuals with diagnosed incident hypertension had increased to 24.4% (95%CI 15.9, 35.4). Increases in treatment (23.3%, 95%CI 15.0, 34.3) and control (22.1%, 95%CI 14.1, 33.0) were also observed, translating to a decrease in unmet need for hypertension care from 92.9% in 2011 to 77.9% in 2017. Multivariable regression showed that participants with incident hypertension in 2017 were 3.01 (95%CI 1.77, 5.13) times more likely to have a controlled blood pressure compared to those in 2011. Our data show that while substantial improvements in the hypertension care cascade occurred between 2011 and 2017, a large burden of unmet need remains. The greatest losses in the incident hypertension care cascades came before diagnosis. Nevertheless, whole system programming will be needed to sufficiently address significant morbidity and mortality related to having an elevated blood pressure.

Identifiers

PMID37676845
PMCPMC10484448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.