Evidence map›Paper›PMID 37676758›Full record

ArticleAmerican journal of physiology. Renal physiology2023

Renal tubular SGK1 is required to achieve blood pressure surge and circadian rhythm.

Olivier Staub, Anne Debonneville, Matteo Stifanelli, Alexandria Juffre, Marc P Maillard, Michelle L Gumz, Lama Al-Qusairi

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  3. Cells · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Olivier StaubDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-1799-9784
Anne DebonnevilleDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-2259-8595
Matteo StifanelliDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.
Alexandria JuffreDivision of Nephrology, Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, Florida, United States.
Marc P MaillardDivision of Nephrology, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0001-6428-0046
Michelle L GumzDivision of Nephrology, Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, Florida, United States.ORCID 0000-0002-1342-0878
Lama Al-QusairiDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-2956-2811
University of Lausanne · CHUniversity of Florida · USJohns Hopkins University · US

Funding

Per1 and the kidney clock in hypertensionR01DK109570 · NIDDK · UNIVERSITY OF FLORIDA · PI GUMZ, MICHELLE L · 2017 to 2021
$1.5M
NIDDK NIH HHS R01 DK109570
6 · The paper itself

Abstract

Blood pressure (BP) follows a circadian pattern that rises during the active phase of the day (morning surge) and decreases during the inactive (night dipping) phase of the day. The morning surge coincides with increased circulating glucocorticoids and aldosterone, ligands for glucocorticoid receptors and mineralocorticoid receptors, respectively. Serum- and glucocorticoid-induced kinase 1 (

Indexed as

AldosteroneGlucocorticoidsAnimalsBlood PressureCircadian RhythmHumansKidneyMiceSerum-Glucocorticoid Regulated KinasesAldosteroneGlucocorticoidsSerum-Glucocorticoid Regulated Kinasesaldosteronecircadian rhythmkidneyserum- and glucocorticoid-induced kinase 1surge

Identifiers

PMID37676758
PMCPMC10878722
OpenAlexW4386498987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.