Evidence map›Paper›PMID 37676420›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2023

Ertapenem plus meropenem combination treatment in carbapenem-resistant Klebsiella pneumoniae bacteremia: an analysis of 53 cases.

Uğur Önal, Deniz Akyol, Arda Kaya, Dilşah Başkol, Buse Kenanoglu, Gamze Şanlıdağ, Ayşe Uyan Önal, Cansu Bulut Avşar, Merve Mert, Seichan Memetali and 14 more

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 3 countries.

Uğur ÖnalDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey. uguronal@uludag.edu.tr.ORCID http://orcid.org/0000-0001-6194-3254
Deniz AkyolDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Arda KayaDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Dilşah BaşkolDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Buse KenanogluDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Gamze ŞanlıdağDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Ayşe Uyan ÖnalDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Cansu Bulut AvşarDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Merve MertDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Seichan MemetaliDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Hüseyin Aytaç ErdemDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Devrim BozkurtDepartment of Internal Medicine, Ege University Faculty of Medicine, Izmir, Turkey.
Adnan ŞimşirDepartment of Urology, Ege University Faculty of Medicine, Izmir, Turkey.
Osman BozbıyıkDepartment of General Surgery, Ege University Faculty of Medicine, Izmir, Turkey.
Ümit KahramanDepartment of Cardiovascular Surgery, Ege University Faculty of Medicine, Izmir, Turkey.
Erkin ÖzgirayDepartment of Neurosurgery, Ege University Faculty of Medicine, Izmir, Turkey.
Pervin KorkmazDepartment of Chest Diseases, Ege University Faculty of Medicine, Izmir, Turkey.
Feriha ÇilliDepartment of Medical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey.
Hüsnü PullukçuDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Tansu YamazhanDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Meltem Işıkgöz TaşbakanDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Bilgin ArdaDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Sercan UlusoyDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Oğuz Reşat SipahiDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Ege University · TRBursa Uludağ Üni̇versi̇tesi̇ · TRIzmir University · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we aimed to describe the outcomes of patients with blood stream infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) who received ertapenem plus meropenem combination treatment (EMCT). A total of 53 patients with culture proven CR-Kp bacteremia treated with ertapenem + meropenem were included. The patients with secondary bacteremia due to urinary tract infection exhibited a significantly lower 1-month mortality (OMM), particularly in those with microbiological eradication and those with end-of-treatment success. Salvage EMCT resulted in 49% 1-month survival.

Indexed as

BacteremiaCarbapenem-Resistant EnterobacteriaceaeErtapenemHumansKlebsiella pneumoniaeMeropenemSalvage TherapyErtapenemMeropenemBacteremiaCarbapenem-resistant Klebsiella pneumoniaDouble carbapenem therapy

Identifiers

PMID37676420
OpenAlexW4386501739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.