Evidence map›Paper›PMID 37675233›Full record

ArticleFrontiers in oncology2023

Nodular cutaneous metastasis of the leg in advanced urothelial bladder carcinoma: a case report and systematic literature review.

Paolo Izzo, Luciano Izzo, Silvia Lai, Giuliano D'Onghia, Paola Giancontieri, Raimondo Gabriele, Andrea Polistena, Simone Sibio, Maria Ludovica Costanzo, Claudia De Intinis and 1 more

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Paolo Izzo"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Luciano Izzo"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Silvia LaiDepartment of Translational and Precision Medicine, Nephrology Unit, Sapienza University of Rome, Rome, Italy.
Giuliano D'Onghia"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Paola GiancontieriDepartment of Radiological, Oncological and Anatomo-Pathological Sciences, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Raimondo Gabriele"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Andrea Polistena"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Simone Sibio"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Maria Ludovica Costanzo"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Claudia De Intinis"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, Rome, Italy.
Sara IzzoMultidisciplinary Department of Medical-Surgical and Dental Specialties, Plastic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, Naples, Italy.
Sapienza University of Rome · ITPoliclinico Umberto I · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous metastases from urothelial carcinoma (UC) are very rare and indicate advanced disease with a poor prognosis. A 63-year-old female patient with a history of urothelial bladder carcinoma, treated 2 months prior with radical cystectomy and adjuvant gemcitabine and cisplatin (GC) therapy, presented a skin lesion localized in the lower third of the right leg. Punch biopsy revealed carcinomatous metastasis whose urothelial origin was confirmed by immunohistochemical analysis. 18-FDG PET-CT showed the spread of metastases to the lung and left ischium. Our review focuses on the time between surgery and skin metastasis, localization, and prognosis after metastasis diagnosis. In many cases, skin metastases occur within one year of initial UC surgery and in most cases occur on the abdominal wall. Local wide excision of metastasis should be considered in selected cases; however, chemotherapy remains the main treatment.

Indexed as

bladdercancercutaneouscutaneous metastasismetastasissystematic literature reviewurothelialurothelial bladder carcinoma

Identifiers

PMID37675233
PMCPMC10477776
OpenAlexW4386073756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.