Evidence map›Paper›PMID 37674885›Full record

ArticleFrontiers in nutrition2023

Body composition parameters correlate with the endoscopic severity in Crohn's disease patients treated with infliximab.

Wuli Tang, Gang Xie, Junlin Li, Wei Tan, Rongqi Yi, Ling Yang, Lingqin Zhang, Jiaxing Deng, Yue Zhang, Kang Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Sarcopenia and frailty in inflammatory bowel disease: Emerging concepts and evidence.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wuli TangChongqing Medical University, Chongqing, China.
Gang XieDepartment of Radiology, The Third People's Hospital of Chengdu, Chengdu, China.
Junlin LiDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Wei TanDepartment of Gastroenterology, Chongqing General Hospital, Chongqing, China.
Rongqi YiDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Ling YangDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Lingqin ZhangDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Jiaxing DengDepartment of General Medicine, Chongqing General Hospital, Chongqing, China.
Yue ZhangDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Kang LiChongqing Medical University, Chongqing, China.
First People's Hospital of Chongqing · CNChongqing Institute of Green and Intelligent Technology · CNChengdu Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The disease activity status and behavior of Crohn's disease (CD) can reflect the severity of the disease, and changes in body composition are common in CD patients. Aims: The aim of this study was to investigate the relationship between body composition parameters and disease severity in CD patients treated with infliximab (IFX). Methods: Patients with CD assessed with the simple endoscopic score (SES-CD) and were treated with IFX were retrospectively collected, and body composition parameters at the level of the 3rd lumbar vertebrae were calculated from computed tomography (CT) scans of the patients. The correlation of patients' body composition parameters with disease activity status and disease behavior was analyzed, and the diagnostic value of the relevant parameters was assessed using receiver operating characteristic (ROC) curves. Results: A total of 106 patients were included in this study. There were significant differences in the subcutaneous adiposity index (SAI) ( Conclusion: Body composition parameters of CD patients treated with IFX correlate with the endoscopic disease severity, and SMI can be used as a reliable indicator of disease activity status.

Indexed as

body compositionCrohn’s diseasedisease activity statusdisease behaviormalnutrition

Identifiers

PMID37674885
PMCPMC10478258
OpenAlexW4386067595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.