Evidence map›Paper›PMID 37674840›Full record

ArticleHeliyon2023

Urinary concentrations of polycyclic aromatic hydrocarbon metabolites and childhood obesity.

Shin-Hye Kim, Mi Jung Park, Sung Kyun Park

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Examining the Link between Air Quality (PM, SOJournal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shin-Hye KimDepartment of Pediatrics, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, South Korea.
Mi Jung ParkDepartment of Pediatrics, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, South Korea.
Sung Kyun ParkDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Inje University Sanggye Paik Hospital · KRUniversity of Michigan · US

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
The Study of the Environment and Alzheimer's disease and related Dementias (SEAD)R01AG070897 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BAKULSKI, KELLY, PARK, SUNG KYUN · 2021 to 2025
$3.4M
Integrated exposome profiling to identify environmental risk factors of metabolic disease in mid- and late-lifeR01ES035087 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sung Kyun Park · 2023 to 2026
$2.5M
Exposure to Multipollutants and Obesity, Type-2 Diabetes and Metabolic SyndromeR01ES026578 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PARK, SUNG KYUN · 2016 to 2020
$2.4M
NIA NIH HHS R01 AG070897NIDDK NIH HHS P30 DK092926NIEHS NIH HHS P30 ES017885NIEHS NIH HHS R01 ES026578NIEHS NIH HHS R01 ES035087
6 · The paper itself

Abstract

Objectives: Existing literature provides limited information on the association between childhood obesity and polycyclic aromatic hydrocarbons (PAHs), which are potentially obesogenic. We examined the association between urinary concentrations of PAH metabolites and obesity in the Korean pediatric population. Methods: We analyzed the data of 2286 children/adolescents aged 3-17 years who participated in the Korean National Environmental Health Survey between 2015 and 2017. Urinary concentrations of 2-naphthol, 2-hydroxyfluorene, 1-hydroxyphenanthrene, and 1-hydroxypyrene were assayed using gas chromatography-mass spectrometry. Overweight/obesity was defined as a body mass index (BMI) for age ≥85th percentile. Multiple linear and logistic regression models were used to analyze the relationship of BMI z-score and overweight with urinary concentrations of PAH metabolites after adjusting for age, sex, household income, parental education level, physical activity, fast-food consumption, and environmental tobacco smoke exposure. Results: BMI z-score was positively associated with 2-naphthol concentrations in children aged 6-11 and 12-17 years and with 1-hydroxypyrene concentrations in children aged 6-11 years. In the overall population, a significant rise in odds ratios for overweight/obesity across 2-naphthol quartiles was noted. Specifically, the 3rd and 4th quartiles displayed odds ratios of 1.39 [1.03, 1.88] and 1.46 [1.08, 1.99] respectively, compared to the 1st quartile (P-for-trend = 0.006). Similar associations between 2-naphthol and overweight/obesity status were observed in the 6-11- and 12-17-year age groups. There was little evidence of an association between overweight/obesity and other PAH hydroxy derivatives. Conclusions: PAH exposure may be associated with increased childhood adiposity, a potential risk factor for adult obesity and adverse metabolic outcomes.

Indexed as

BiomonitoringEndocrine disruptorsKoreaPediatric obesity

Identifiers

PMID37674840
PMCPMC10477474
OpenAlexW4386052558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.