ArticleFrontiers in aging neuroscience2023
Sleep duration and age-related macular degeneration: a cross-sectional and Mendelian randomization study.
Article in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Association of baseline brain care score with the incidence of age-related eye diseases.Eye (London, England) · 2026Article
- Association between trouble sleeping and cataract in US adults: a cross-sectional study.Frontiers in medicine · 2026Article
- Association Between Eye Diseases and Sleep Duration: A Nationwide Cross-Sectional Study.Psychiatry investigation · 2025Article
- Identification of Biomarkers for Oxidative Stress in Age-Related Macular Degeneration: Combining Transcriptomics and Mendelian Randomization Analysis.Translational vision science & technology · 2025Article
- Life's Essential 8, Genetic Susceptibility, and the Risk of Age-Related Macular Degeneration: A Prospective Cohort Study.Investigative ophthalmology & visual science · 2025Article
- Associations of Cardiovascular Health and New-Onset Age-Related Macular Diseases From UK Biobank.Investigative ophthalmology & visual science · 2025Article
- New Perspective on Aqueous Humor Circulation: Retina Takes the Lead.International journal of molecular sciences · 2025Review
- A cross-sectional observational study of the association between biochemistry profiles and the risk of age-related macular degeneration.Scientific reports · 2025Observational
- The Effect of Partial Sleep Deprivation on Retinal Microvasculature in Myopia With Different Axial Lengths.Investigative ophthalmology & visual science · 2025Article
- Modifiable Lifestyle Risk Factors and Strategies for Slowing the Progression of Age-Related Macular Degeneration.Vision (Basel, Switzerland) · 2025Review
- The severity of depressive symptoms as a mediator in the sleep-osteoarthritis risk pathway: insights from the ELSA cohort.Frontiers in nutrition · 2025Article
- Age-Related Macular Degeneration and Circadian Preference.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Non-linear association of sleep duration with osteoarthritis among U.S. middle-aged and older adults.BMC public health · 2024Article
- The causal effects of lifestyle, circulating, pigment, and metabolic factors on early age-related macular degeneration: a comprehensive Mendelian randomization study.Journal of translational medicine · 2024Article
- Causal Links between Gut Microbiota, Blood Metabolites, Immune Cells, Inflammatory Proteins, and Myopia: A Mendelian Randomization Study.Ophthalmology scienceArticle
- Association between regular hypnotic use and age-related macular degeneration.Advances in ophthalmology practice and researchArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the association between sleep duration and age-related macular degeneration (AMD). Design: Cross-sectional study, bidirectional two-sample Mendelian randomization (MR). For cross-sectional analysis, we used survey data of 5,481 participants aged ≥40 years from the 2005 to 2008 National Health and Nutrition Examination Survey (NHANES). For MR analysis, we used sleep- and AMD-associated genome-wide association studies (GWAS) data involving large populations. Methods: The association between sleep duration and AMD was assessed using logistic regression models. For MR analysis, the primary approach for MR analysis was the inverse-variance weighted (IVW) method. Results: In cross-sectional analysis, after adjusting for multiple covariates, short sleep duration (SSD) was found to be associated with increased risk of early AMD [odds ratio (OR) = 1.364, Conclusion: Our findings provide the evidence supporting the association between sleep deficiency and higher risk of AMD. Further studies are required to confirm our findings and elucidate the mechanisms underlying this association.
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