Evidence map›Paper›PMID 37674633›Full record

ArticleOpen forum infectious diseases2023

Stillbirths and Neonatal Deaths Caused by Group B

Sana Mahtab, Zachary J Madewell, Shabir A Madhi, Amy Wise, Peter J Swart, Sithembiso Velaphi, Inacio Mandomando, Justina Bramugy, Rita Mabunda, Elisio Xerinda and 32 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. PhenoMATRIX™ for the screening of Group B Streptococcus (GBS) carriage in pregnant women: ready to get rid of the LIM broth?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. Observational
  11. Article
  12. Observational
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  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 10 countries.

Sana MahtabSouth African Medical Research Council, Vaccines Infectious Diseases and Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Zachary J MadewellCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Shabir A MadhiSouth African Medical Research Council, Vaccines Infectious Diseases and Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Amy WiseNational Health for Laboratory Service in South Africa, Johannesburg, South Africa.
Peter J SwartDepartment of Obstetrics and Gynecology, Rahima Mossa Mother and Child Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Sithembiso VelaphiDepartment of Pediatrics, Chris Hani Baragwanath Academic Hospital, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Inacio MandomandoCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Justina BramugyCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Rita MabundaISGlobal-Hospital Clínic, Unversitat de Barcelona, Barcelona, Spain.
Elisio XerindaCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Anthony G ScottDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Nega AssefaCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Lola MadridDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Mulu BweihunAddis Ababa University, Addis Ababa, Ethiopia.
Fikremelekot TemesgenAddis Ababa University, Addis Ababa, Ethiopia.
Dickens OnyangoKisumu County Department of Health, Ministry of Health, Kisumu, Kenya.
Victor AkeloUS Centers for Disease Control and Prevention-Kenya, Kisumu, Kenya.
Richard OliechKenya Medical Research Institute-Center for Global Health Research (KEMRI-CGHR), Kisumu, Kenya.
Peter OtienoKenya Medical Research Institute-Center for Global Health Research (KEMRI-CGHR), Kisumu, Kenya.
Jennifer R VeraniNational Center for Immunization and Respiratory Disease, Centers for Disease Control, Atlanta, Georgia, USA.
Shams El ArifeenInternational Center for Diarrhoeal Diseases Research (icddr, b), Dhaka, Bangladesh.
Emily S GurleyInternational Center for Diarrhoeal Diseases Research (icddr, b), Dhaka, Bangladesh.
Muntasir AlamInternational Center for Diarrhoeal Diseases Research (icddr, b), Dhaka, Bangladesh.
Afruna RahmanInternational Center for Diarrhoeal Diseases Research (icddr, b), Dhaka, Bangladesh.
Mohammad Zahid HossainInternational Center for Diarrhoeal Diseases Research (icddr, b), Dhaka, Bangladesh.
Samba SowCentre pour le Développement des Vaccins (CVD-Mali), Ministère de la Santé, Bamako, Mali.
Karen KotloffCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Milagritos TapiaCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Adama Mamby KeitaCentre pour le Développement des Vaccins (CVD-Mali), Ministère de la Santé, Bamako, Mali.
Doh SanogoCentre pour le Développement des Vaccins (CVD-Mali), Ministère de la Santé, Bamako, Mali.
Ikechukwu OgbuanuCrown Agents, Freetown, Sierra Leone.
Julius OjulongICAP-Columbia University, Makeni, Sierra Leone.
Sandra LakoAberdeen Women's Centre in Freetown, Sierra Leone.
Okokon ItaCrown Agents, Freetown, Sierra Leone.
Erick KalumaCrown Agents, Freetown, Sierra Leone.
Tais WilsonCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Portia MutevedziEmory Global Health Institute, Emory University, Atlanta, Georgia, USA.
Beth A Tippett BarrKenya Medical Research Institute-Center for Global Health Research (KEMRI-CGHR), Kisumu, Kenya.
Cynthia G WhitneyEmory Global Health Institute, Emory University, Atlanta, Georgia, USA.
Dianna M BlauCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Quique BassatCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
CHAMPS Consortium
Kenya Medical Research Institute · KECentre Pour le Développement des Vaccins-Mali · MLUniversity of the Witwatersrand · ZAInternational Centre for Diarrhoeal Disease Research · BDManhiça Health Research Centre · MZAddis Ababa University · ETCenters for Disease Control and Prevention · USSierra Leone Urban Research Centre · SLEmory University · USHaramaya University · ETJohns Hopkins University · USSouth African Medical Research Council · ZAUniversity of Maryland, Baltimore · USBarcelona Institute for Global Health · ESCenters for Disease Control and Prevention · KEInstitució Catalana de Recerca i Estudis Avançats · ESLondon School of Hygiene & Tropical Medicine · GBMaisha Meds · KENational Center for Immunization and Respiratory Diseases · USNational Health Laboratory Service · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive Group B Methods: Deaths that occurred between December 2016 and December 2021 were investigated with MITS, including culture for bacteria of blood and cerebrospinal fluid (CSF), multipathogen polymerase chain reaction on blood, CSF, and lung tissue and histopathology of lung, liver, and brain. Data collection included clinical record review and verbal autopsy. Expert panels reviewed all information and assigned causes of death. Results: We evaluated 2966 deaths, including stillborn infants ( Conclusions: Our study reveals significant heterogeneity in the contribution of invasive GBS disease to infant mortality across different countries, emphasizing the need for tailored prevention strategies. Moreover, our findings highlight the substantial impact of GBS on stillbirths, shedding light on a previously underestimated aspect in LMICs.

Indexed as

death in 24 hoursearly neonatal death, stillbirthminimally invasive tissue sampling (MITS)Streptococcus agalactiae

Identifiers

PMID37674633
PMCPMC10478157
OpenAlexW4383874079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.