Evidence map›Paper›PMID 37674528›Full record

ArticleCancer research communications2023

Single-cell Profiling Uncovers a

Valerie P O'Brien, Yuqi Kang, Meera K Shenoy, Greg Finak, William C Young, Julien Dubrulle, Lisa Koch, Armando E Rodriguez Martinez, Jeffery Williams, Elizabeth Donato and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancer research communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Diet-Induced Obesity ExacerbatesbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Managing dangerous liaisons: lessons fromJournal of bacteriology · 2026
    Review
  5. Metaplasia Enables Stomach Colonization bybioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Highlights of how single-cell analyses are illuminating differentiation and disease in the gastric corpus.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Valerie P O'BrienHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0003-0502-2690
Yuqi KangHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0003-0246-248X
Meera K ShenoyBasic Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-3986-1321
Greg FinakVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0003-4341-9090
William C YoungVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-3368-052X
Julien DubrulleShared Resources, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-4186-7749
Lisa KochDivision of Gastrointestinal and Hepatic Pathology, University of Washington Medical Center, Seattle, Washington.ORCID 0000-0002-3890-9290
Armando E Rodriguez MartinezHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0009-0006-7336-7243
Jeffery WilliamsShared Resources, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0009-0003-7556-6471
Elizabeth DonatoTranslational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0009-0002-4517-8278
Surinder K BatraDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska.ORCID 0000-0001-9470-9317
Cecilia C S YeungTranslational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0001-6799-2022
William M GradyTranslational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-0129-7809
Meghan A KochBasic Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-9539-4027
Raphael GottardoVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0002-3867-0232
Nina R SalamaHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington.ORCID 0000-0003-2762-1424
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAFred Hutch Cancer Center · USUniversity of Nebraska Medical Center · USUniversity of Washington · USUniversity of Washington Medical Center · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
GENETIC REQUIREMENTS OF HELICOBACTER PYLORI INFECTIONR01AI054423 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Nina Salama · 2004 to 2026
$9.5M
Gastrointestinal microbiota interactions modulating gastric cancer progressionR21CA270512 · NCI · FRED HUTCHINSON CANCER CENTER · PI SALAMA, NINA · 2022 to 2023
$443k
Investigating gastric inflammation and preneoplastic progression driven by Helicobacter pylori infectionK99CA263036 · NCI · FRED HUTCHINSON CANCER CENTER · PI O'BRIEN, VALERIE PHOEBE · 2022 to 2023
$336k
NCI NIH HHS K99 CA263036NCI NIH HHS P30 CA015704NCI NIH HHS R21 CA270512NIAID NIH HHS R01 AI054423
6 · The paper itself

Abstract

Mechanisms for Significance: Using a mouse model, we have delineated metaplastic pit cells as a precancerous cell type whose expansion requires

Indexed as

Helicobacter pyloriStomach NeoplasmsAnimalsDisease Models, AnimalHumansInflammationMiceProto-Oncogene Proteins p21(ras)Proto-Oncogene Proteins p21(ras)

Identifiers

PMID37674528
PMCPMC10478791
OpenAlexW4385806338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.