Evidence map›Paper›PMID 37674503›Full record

ReviewJournal of the Canadian Association of Gastroenterology2023

The 2023 Impact of Inflammatory Bowel Disease in Canada: Special Populations-IBD in Seniors.

Seth R Shaffer, M Ellen Kuenzig, Joseph W Windsor, Alain Bitton, Jennifer L Jones, Kate Lee, Sanjay K Murthy, Laura E Targownik, Juan-Nicolás Peña-Sánchez, Noelle Rohatinsky and 18 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the Canadian Association of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The global burden of inflammatory bowel disease: from 2025 to 2045.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 13 institutions in 1 country.

Seth R ShafferDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
M Ellen KuenzigSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3984-8426
Joseph W WindsorDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-7539-9103
Alain BittonDivision of Gastroenterology and Hepatology, McGill University Health Centre IBD Centre, McGill University, Montréal, Quebec, Canada.
Jennifer L JonesDepartments of Medicine, Clinical Health, and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Kate LeeCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Sanjay K MurthyDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Laura E TargownikDivision of Gastroenterology and Hepatology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-4366-9076
Juan-Nicolás Peña-SánchezDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0002-4653-525X
Noelle RohatinskyCollege of Nursing, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0003-3052-027X
Sara GhandeharianCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Parul TandonDivision of Gastroenterology and Hepatology, University Health Network, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-0021-2161
Joëlle St-PierreDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Navneet NattNorthern Ontario School of Medicine University, Sudbury, Ontario, Canada.
Tal DavisSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jake WeinsteinSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
James H B ImSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Eric I BenchimolSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-8855-3598
Gilaad G KaplanDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-2719-0556
Quinn GoddardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Julia GorospeDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Maxime BergevinÉcole de kinésiologie et des sciences de l'activité physique, Faculté de médecine, Université́ de Montréal, Montreal, Quebec, Canada.
Ken SilverCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Dawna BowlesCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Margaret StewartCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Marsha PearlsteinCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Elizabeth H DawsonCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Charles N BernsteinDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-8041-3574
Crohn's and Colitis Canada · CAUniversity of Calgary · CASickKids Foundation · CAUniversity of Manitoba · CAUniversity of Saskatchewan · CADalhousie University · CAInstitut Universitaire de Gériatrie de Montréal · CAMcGill University Health Centre · CAMount Sinai Hospital · CANOSM University · CAUniversity Health Network · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately one out of every 88 seniors has inflammatory bowel disease (IBD), and this is expected to increase in the future. They are more likely to have left-sided disease in ulcerative colitis, and isolated colonic disease in Crohn's disease; perianal disease is less common. Other common diagnoses in the elderly must also be considered when they initially present to a healthcare provider. Treatment of the elderly is similar to younger persons with IBD, though considerations of the increased risk of infections and malignancy must be considered when using immune modulating drugs. Whether anti-TNF therapies increase the risk of infections is not definitive, though newer biologics, including vedolizumab and ustekinumab, are thought to be safer with lower risk of adverse events. Polypharmacy and frailty are other considerations in the elderly when choosing a treatment, as frailty is associated with worse outcomes. Costs for IBD-related hospitalizations are higher in the elderly compared with younger persons. When elderly persons with IBD are cared for by a gastroenterologist, their outcomes tend to be better. However, as elderly persons with IBD continue to age, they may not have access to the same care as younger people with IBD due to deficiencies in their ability to use or access technology.

Indexed as

ComorbidityCrohn’s diseaseElderlyRisksUlcerative colitis

Identifiers

PMID37674503
PMCPMC10478801
OpenAlexW4386465677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.