ReviewJournal of the Canadian Association of Gastroenterology2023
The 2023 Impact of Inflammatory Bowel Disease in Canada: Executive Summary.
Review in Journal of the Canadian Association of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07169123 (Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD), which is not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD
Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- A qualitative evaluation of treatment fidelity alongside a pilot trial of a novel therapy for pediatric Inflammatory Bowel Disease.PloS one · 2024Trial
- Review
- The Impact of Informal Caregiving on Patient-Reported Outcomes, Psychological Well-Being and Quality of Life in Inflammatory Bowel Disease: A Systematic Review.Nursing reports (Pavia, Italy) · 2026Review
- Cost-Consequences Analysis of Biologic Treatments for Moderate-to-Severe Crohn's Disease Using Real-World Transition Probability and Cost Data in Thailand.Clinical drug investigation · 2026Article
- Pooled prevalence of psychological distress and mental health conditions in older adults with inflammatory bowel disease: a protocol for a systematic review and meta-analysis.Systematic reviews · 2026Article
- Crohn's and bones: assessing bone microarchitecture using high-resolution peripheral quantitative computed tomography.JBMR plus · 2026Article
- Accuracy of Bowel Ultrasound for Detecting Inflammatory Bowel Disease at a Tertiary Hospital in Central South Africa.Journal of clinical ultrasound : JCU · 2026Article
- Strain-dependent efficacy of pasteurizedFrontiers in nutrition · 2026Article
- The Impact of Proactive Fecal Calprotectin Collection in an Outreach Protocol for Biologic-Naïve Ulcerative Colitis Patients-Ulcerative Colitis Clinical Outreach (UCCO).Diseases (Basel, Switzerland) · 2025Article
- The global burden of inflammatory bowel disease: from 2025 to 2045.Nature reviews. Gastroenterology & hepatology · 2025Review
- Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.medRxiv : the preprint server for health sciences · 2025Article
- A framework for clinical care pathway renewal: an example from inflammatory bowel disease.BMC medical research methodology · 2025Article
- A multivariable prediction model to stratify risk of 90-day rehospitalization among adults with ulcerative colitis.Journal of the Canadian Association of Gastroenterology · 2025Article
- Gender Differences in Coping Strategies and Life Satisfaction Following Cognitive-Behavioral and Mindfulness-Based Intervention for Crohn's Disease: A Randomized Controlled Trial.Journal of clinical medicine · 2025Article
- Article
- Mycophenolate Mofetil Appears Effective for the Treatment of Patients With Refractory Crohn's Disease.Crohn's & colitis 360 · 2024Article
- Identification and prioritization of patient-centred strategies to enhance IBD-related care for older adults: a modified Delphi approach.Journal of the Canadian Association of Gastroenterology · 2024Article
- Novel 5-HTAmerican journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Patient and Public Involvement in Inflammatory Bowel Disease Research-A Scoping Review.Journal of the Canadian Association of Gastroenterology · 2024Article
- Chia nanoemulsion: anti-inflammatory mechanism, biological behavior and cellular interactions.Therapeutic delivery · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
17 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The burden of inflammatory bowel disease (IBD) (i.e., associated direct and indirect costs, prevalence of disease, personal impact to the individual and to caregivers) continues to increase in Canada. The prevalence of IBD has increased since Crohn's and Colitis Canada's 2018 Impact of IBD report from an estimated 270,000 Canadians living with IBD in 2018 to an estimated 322,600 Canadians living with IBD today in 2023. Consequently, associated costs of IBD have also dramatically increased from an estimated $2.57 billion in 2018 to an estimated $5.38 billion in 2023; this increase is due to multiple factors including increased prevalence of disease, inflation, and additional identified factors (e.g., presenteeism, costs of childcare). Beyond the economic impact of IBD, these diseases have a significant impact on people living with the disease and their caregivers, including different presentations of disease, different commonly associated extra-intestinal manifestations or comorbid conditions, and different barriers to accessing care. In this supplementary issue, we review: Evolving trends in the epidemiology of IBD; updated estimates of indirect and direct costs (including out-of-pocket costs) associated with IBD; information specific to IBD in children, adolescents, and seniors; issues related to IBD pertaining to sex and gender; information specific to risks associated with COVID-19 and cancer related to IBD; an overview of current treatments for IBD; and evolving care models, including access to care.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.