Evidence map›Paper›PMID 37674499›Full record

ReviewJournal of the Canadian Association of Gastroenterology2023

The 2023 Impact of Inflammatory Bowel Disease in Canada: Mental Health and Inflammatory Bowel Disease.

Lesley A Graff, Rose Geist, M Ellen Kuenzig, Eric I Benchimol, Gilaad G Kaplan, Joseph W Windsor, Alain Bitton, Stephanie Coward, Jennifer L Jones, Kate Lee and 21 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the Canadian Association of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Experiences and perceptions of IBD-related psychological distress in persons living with IBD.Journal of the Canadian Association of Gastroenterology · 2026
    Article
  4. Article
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  6. Review
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  12. Models of outpatient care delivery in inflammatory bowel disease: a scoping review.Journal of the Canadian Association of Gastroenterology · 2025
    Article
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 14 institutions in 2 countries.

Lesley A GraffDepartment of Clinical Health Psychology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Rose GeistDepartment of Psychiatry, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
M Ellen KuenzigSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3984-8426
Eric I BenchimolSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-8855-3598
Gilaad G KaplanDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-2719-0556
Joseph W WindsorDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-7539-9103
Alain BittonDivision of Gastroenterology and Hepatology, McGill University Health Centre IBD Centre, McGill University, Montréal, Quebec, Canada.
Stephanie CowardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-0675-7226
Jennifer L JonesDepartments of Medicine, Clinical Health, and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Kate LeeCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Sanjay K MurthyDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Juan-Nicolás Peña-SánchezDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0002-4653-525X
Laura E TargownikDivision of Gastroenterology and Hepatology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-4366-9076
Nazanin JannatiDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Tyrel Jones MayDivision of Gastroenterology and Hepatology, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Tasbeen Akhtar SheekhaDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Tal DavisSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jake WeinsteinSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ghaida DahlwiSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
James H B ImSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jessica Amankwah OseiDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Noelle RohatinskyCollege of Nursing, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0003-3052-027X
Sara GhandeharianCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Quinn GoddardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Julia GorospeDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Shira GertsmanMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Michelle LouisCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Richelle WagnerDepartment of Educational Psychology, University of Alberta, Edmonton, Alberta, Canada.
Colten BrassMuskoday First Nation, Saskatchewan, Canada.
Rhonda SandersonJames Smith Cree Nation, Saskatchewan, Canada.
Charles N BernsteinUniversity of Manitoba IBD Clinical and Research Centre, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-8041-3574
University of Calgary · CAUniversity of Saskatchewan · CASickKids Foundation · CACrohn's and Colitis Canada · CAUniversity of Manitoba · CAUniversity of Toronto · CADalhousie University · CAKing Abdulaziz University · SAMcGill University Health Centre · CAMcMaster University · CAMount Sinai Hospital · CAUniversity Health Network · CAUniversity of Alberta · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychiatric disorders are 1.5 to 2 times more prevalent in persons with inflammatory bowel disease (IBD) than in the general population, with pooled prevalence estimates of 21% for clinical anxiety and 15% for depression. Rates are even higher when considering mental health symptoms, as nearly one-third of persons with IBD experience elevated anxiety symptoms and one-quarter experience depression symptoms. Rates of these symptoms were much higher during periods of disease activity, more common in women than men, and more common in Crohn's disease than ulcerative colitis. There is robust evidence of the detrimental effects of comorbid depression and anxiety on the subsequent course of IBD based on longitudinal studies tracking outcomes over time. However, psychiatric disorders and IBD have bidirectional effects, with each affecting risk of the other. Elevated mental health concerns have been consistently associated with greater healthcare utilization and costs related to IBD. There is some signal that low resilience in adolescence could be a risk factor for developing IBD and that enhancing resilience may improve mental health and intestinal disease outcomes in IBD. Psychological therapies used to treat anxiety and depression occurring in the context of IBD have been shown to significantly improve the quality of life for persons with IBD and reduce anxiety and depression. There is less evidence in regard to the impact of psychotropic medications on mental health or disease outcomes in persons with IBD. There is consensus, however, that mental health must be addressed as part of comprehensive IBD care for children and adults.

Indexed as

AnxietyCrohn’s diseaseDepressionMental healthUlcerative colitis

Identifiers

PMID37674499
PMCPMC10478810
OpenAlexW4386457006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.