Evidence map›Paper›PMID 37674497›Full record

ReviewJournal of the Canadian Association of Gastroenterology2023

The 2023 Impact of Inflammatory Bowel Disease in Canada: Special Populations-Children and Adolescents with IBD.

Wael El-Matary, Matthew W Carroll, Colette Deslandres, Anne M Griffiths, M Ellen Kuenzig, David R Mack, Eytan Wine, Jake Weinstein, Rose Geist, Tal Davis and 23 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the Canadian Association of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 14 institutions in 1 country.

Wael El-MataryDepartment of Pediatrics and Child Health, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-6417-7583
Matthew W CarrollDivision of Pediatric Gastroenterology and Nutrition, University of Alberta, Edmonton, Alberta, Canada.
Colette DeslandresDepartment of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
Anne M GriffithsSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
M Ellen KuenzigSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3984-8426
David R MackCHEO IBD Centre and Department of Pediatrics, University of Ottawa, Ottawa, Canada.
Eytan WineDepartments of Pediatrics and Physiology, University of Alberta, Edmonton, Alberta, Canada.
Jake WeinsteinSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Rose GeistDepartment of Psychiatry, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
Tal DavisSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Justin ChanDepartment of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, British Columbia Children Hospital Research Institute, Vancouver, British Columbia, Canada.
Rabia KhanSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Priscilla MatthewsDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Gilaad G KaplanDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-2719-0556
Joseph W WindsorDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-7539-9103
Charles N BernsteinDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-8041-3574
Alain BittonDivision of Gastroenterology and Hepatology, McGill University Health Centre, IBD Centre, McGill University, Montréal, Quebec, Canada.
Stephanie CowardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-0675-7226
Jennifer L JonesDepartments of Medicine, Clinical Health, and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Kate LeeCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Sanjay K MurthyDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Laura E TargownikDivision of Gastroenterology and Hepatology, Mount Sinai Hospital, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-4366-9076
Juan-Nicolás Peña-SánchezDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0002-4653-525X
Noelle RohatinskyCollege of Nursing, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0003-3052-027X
Sara GhandeharianCrohn's and Colitis Canada, Toronto, Ontario, Canada.
James H B ImSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Quinn GoddardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Julia GorospeDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Jules VerdugoCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Samantha A MorinDepartment of Medical Sciences, McMaster University, Hamilton, Ontario, Canada.
Taylor MorgansteinFaculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada.
Lisa BanningCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Eric I BenchimolSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-8855-3598
SickKids Foundation · CAUniversity of Calgary · CACrohn's and Colitis Canada · CAUniversity of Toronto · CAMcGill University Health Centre · CAMcMaster University · CAUniversity of Alberta · CAUniversity of Manitoba · CAUniversity of Ottawa · CAUniversity of Saskatchewan · CABC Children's Hospital · CACentre Hospitalier Universitaire Sainte-Justine · CADalhousie University · CAMount Sinai Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rates of inflammatory bowel disease (IBD) in Canadian children and adolescents are among the highest in the world, and the incidence is rising most rapidly in children under five years of age. These young children may have either a typical form of IBD with multi-factorial aetiology, or they may have a monogenic form. Despite the growing number of children in Canada living with this important chronic disease, there are few available medical therapies approved by Health Canada due to the omission of children from most clinical trials of newly developed biologics. As a result, off-label use of medications is common, and physicians have learned to use existing therapies more effectively. In addition, most Canadian children are treated in multidisciplinary, specialty clinics by physicians with extra training or experience in IBD, as well as specialist nurses, dietitians, mental health care providers and other allied health professionals. This specialized clinic approach has facilitated cutting edge research, led by Canadian clinicians and scientists, to understand the causes of IBD, the optimal use of therapies, and the best ways to treat children from a biopsychosocial perspective. Canadians are engaged in work to understand the monogenic causes of IBD; the interaction between genes, the environment, and the microbiome; and how to address the mental health concerns and medical needs of adolescents and young adults transitioning from paediatric to adult care.

Indexed as

Crohn’s diseasePaediatricsTransitionUlcerative colitis

Identifiers

PMID37674497
PMCPMC10478811
OpenAlexW4386461704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.