Evidence map›Paper›PMID 37674492›Full record

ReviewJournal of the Canadian Association of Gastroenterology2023

The 2023 Impact of Inflammatory Bowel Disease in Canada: Epidemiology of IBD.

Stephanie Coward, Eric I Benchimol, M Ellen Kuenzig, Joseph W Windsor, Charles N Bernstein, Alain Bitton, Jennifer L Jones, Kate Lee, Sanjay K Murthy, Laura E Targownik and 15 more

Erratum issued Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of the Canadian Association of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06725563 (Endoscopically Placed Lumen-Apposing Metal Stents as a Safe Alternative to Surgery for the Treatment of Symptomatic Intestinal Strictures in Individuals With Inflammatory Bowel Disease), which is not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06725563 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Endoscopically Placed Lumen-Apposing Metal Stents as a Safe Alternative to Surgery for the Treatment of Symptomatic Intestinal Strictures in Individuals With Inflammatory Bowel Disease

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2025 to 2026Enrolled20ConditionsInflammatory Bowel Diseases, Stricture, BowelArmsEndoscopically placed lumen-apposing metal stents for the treatment of IBD-strictures
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  6. Experiences and perceptions of IBD-related psychological distress in persons living with IBD.Journal of the Canadian Association of Gastroenterology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 11 institutions in 1 country.

Stephanie CowardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-0675-7226
Eric I BenchimolSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-8855-3598
M Ellen KuenzigSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3984-8426
Joseph W WindsorDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-7539-9103
Charles N BernsteinDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-8041-3574
Alain BittonDivision of Gastroenterology and Hepatology, McGill University Health Centre IBD Centre, McGill University, Montréal, Quebec, Canada.
Jennifer L JonesDepartments of Medicine, Clinical Health, and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Kate LeeCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Sanjay K MurthyDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Laura E TargownikDivision of Gastroenterology and Hepatology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Juan-Nicolás Peña-SánchezDepartment of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0002-4653-525X
Noelle RohatinskyCollege of Nursing, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0003-3052-027X
Sara GhandeharianCrohn's and Colitis Canada, Toronto, Ontario, Canada.
James H B ImSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Tal DavisSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jake WeinsteinSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.
Quinn GoddardDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Jennifer BennettCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Léa CaplanDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Maxime BergevinÉcole de kinésiologie et des sciences de l'activité physique, Faculté de médecine, Université de Montréal, Montreal, Quebec, Canada.
Xin Yu YangCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Kate MasonCrohn's and Colitis Canada, Toronto, Ontario, Canada.
Rhonda SandersonJames Smith Cree Nation, Saskatchewan, Canada.
Colten BrassMuskoday First Nation, Saskatchewan, Canada.
Gilaad G KaplanDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-2719-0556
University of Calgary · CACrohn's and Colitis Canada · CASickKids Foundation · CAUniversity of Saskatchewan · CADalhousie University · CAInstitut Universitaire de Gériatrie de Montréal · CAMcGill University Health Centre · CAMount Sinai Hospital · CAUniversity of Manitoba · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), consisting of Crohn's disease and ulcerative colitis, is recognized across the world, though Canada has among the highest burdens of IBD in the world. The Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC) led a six-province study that demonstrated the compounding prevalence of IBD in Canada from 400 per 100,000 in 2002 to 636 per 100,000 in 2014. The prevalence in 2023 is estimated at 825 per 100,000, meaning that over 320,000 people in Canada are living with IBD. Prevalence is forecasted to rise by 2.44% per year such that 1.1% of the population, 470,000 Canadians, will live with IBD by 2035. The overall incidence of IBD in 2023 is 30 per 100,000 person-years, indicating that over 11,000 Canadians will be newly diagnosed with IBD in 2023. Incidence is forecasted to rise by 0.58% per year up to 32.1 per 100,000 by 2035. The rising incidence of IBD is propelled by pediatric-onset IBD, which is rising by 1.23% per year from 15.6 per 100,000 in 2023 to 18.0 per 100,000 in 2035. In contrast, incidence rates among adults and seniors are relatively stable. Understanding the determinates of IBD has expanded through prospective cohort studies such as the Crohn's and Colitis Canada Genetic, Environmental, Microbial (CCC-GEM) project. Consensus recommendations towards diet, lifestyle, behavioural and environmental modifications have been proposed by international organizations with the goal of optimizing disease control and ultimately preventing the development of IBD. Despite these efforts, Canadian healthcare systems will need to prepare for the rising number of people living with IBD.

Indexed as

Crohn’s diseaseEpidemiology trendsIncidencePrevalenceUlcerative colitis

Identifiers

PMID37674492
PMCPMC10478802
OpenAlexW4386465662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.