ArticleBJPsych open2023
The structure stability of negative symptoms: longitudinal network analysis of the Brief Negative Symptom Scale in people with schizophrenia.
Article in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Associations between negative symptoms and resting-state functional connectivity within social brain networks among individuals with early psychosis.Schizophrenia (Heidelberg, Germany) · 2026Article
- Persistent negative symptoms in the EULAST cohort: impact on functional outcome.Schizophrenia (Heidelberg, Germany) · 2026Article
- Negative symptoms, cognition, and community functioning in early psychosis.Schizophrenia research · 2025Article
- A transdiagnostic approach of negative symptoms in psychiatric disorders: replication of a two-factor structure in major depressive disorder and bipolar disorder.European archives of psychiatry and clinical neuroscience · 2025Article
- Comparison of Negative Symptom Network Structures Between Patients With Early and Chronic Schizophrenia: A Network and Exploratory Graph Analysis.Schizophrenia bulletin · 2025Article
- Assessment of Negative Symptoms in Schizophrenia: From the Consensus Conference-Derived Scales to Remote Digital Phenotyping.Brain sciences · 2025Review
- Relationship between negative symptoms, cognitive function and social function in schizophrenia: new insight from a network analysis.Frontiers in psychiatry · 2025Article
- Network analysis of clinical features in patients with treatment-resistant schizophrenia.Frontiers in psychiatry · 2025Article
- Current limitations in technology-based cognitive assessment for severe mental illnesses: a focus on feasibility, reliability, and ecological validity.Frontiers in behavioral neuroscience · 2025Review
- Interview Versus Performance Assessment of Cognition as Predictors of Real-World Outcomes in a Large-Scale Cross-Sectional Study in Schizophrenia.Schizophrenia bulletin open · 2024Article
- External validation of the five domains of negative symptoms: Focus on cognition, functional capacity, and real-world functioning.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- [The structural stability of negative symptoms over time].BJPsych open · 2023Article
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Authors and funding
15 authors.
Funding
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Abstract
backgroundThe structure of negative symptoms of schizophrenia is still a matter of controversy. Although a two-dimensional model (comprising the expressive deficit dimension and the motivation and pleasure dimension) has gained a large consensus, it has been questioned by recent investigations.
aimsTo investigate the latent structure of negative symptoms and its stability over time in people with schizophrenia using network analysis.
methodNegative symptoms were assessed in 612 people with schizophrenia using the Brief Negative Symptom Scale (BNSS) at baseline and at 4-year follow-up. A network invariance analysis was conducted to investigate changes in the network structure and strength of connections between the two time points.
resultsThe network analysis carried out at baseline and follow-up, supported by community detection analysis, indicated that the BNSS's items aggregate to form four or five distinct domains (avolition/asociality, anhedonia, blunted affect and alogia). The network invariance test indicated that the network structure remained unchanged over time (network invariance test score 0.13;
conclusionsThe results lend support to a four- or five-factor model of negative symptoms and indicate overall stability over time. These data have implications for the study of pathophysiological mechanisms and the development of targeted treatments for negative symptoms.
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