ArticleRadiation oncology (London, England)2023
Impact of MRI on target volume definition in head and neck cancer patients.
Article in Radiation oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Computed tomography and magnetic resonance imaging radiomics for predicting non-complete response after chemoradiotherapy in unresectable locally advanced head and neck squamous cell carcinoma.Physics and imaging in radiation oncology · 2026Article
- Quantitative magnetic resonance imaging for accurate delineation of radiotherapy: a narrative review.Translational cancer research · 2026Review
- Validation of MRI-based nnU-Net model for automated segmentation of neck lymph nodes in head and neck squamous cell carcinoma: a multicenter study.Neuroradiology · 2026Article
- Impacts of volumetric vs. anatomical accuracies in GTV segmentation for nasopharyngeal carcinoma: a consensus-guideline-based study.Frontiers in medicine · 2026Article
- Adaptive radiotherapy for oropharyngeal cancer with daily adapt-to-shape workflow on 1.5 T MRI-linac: Preliminary outcomes and comparison with helical tomotherapy.Clinical and translational radiation oncology · 2025Article
- Recent innovations in offline and online Magnetic Resonance Imaging guided radiation oncology.Physics and imaging in radiation oncology · 2025Article
- Incidental findings and safety events from magnetic resonance imaging simulation for head and neck radiation treatment planning: A single institution experience.Technical innovations & patient support in radiation oncology · 2024Article
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Authors and funding
6 authors.
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Abstract
backgroundTarget volume definition for curative radiochemotherapy in head and neck cancer is crucial since the predominant recurrence pattern is local. Additional diagnostic imaging like MRI is increasingly used, yet it is usually hampered by different patient positioning compared to radiotherapy. In this study, we investigated the impact of diagnostic MRI in treatment position for target volume delineation.
methodsWe prospectively analyzed patients who were suitable and agreed to undergo an MRI in treatment position with immobilization devices prior to radiotherapy planning from 2017 to 2019. Target volume delineation for the primary tumor was first performed using all available information except for the MRI and subsequently with additional consideration of the co-registered MRI. The derived volumes were compared by subjective visual judgment and by quantitative mathematical methods.
resultsSixteen patients were included and underwent the planning CT, MRI and subsequent definitive radiochemotherapy. In 69% of the patients, there were visually relevant changes to the gross tumor volume (GTV) by use of the MRI. In 44%, the GTV_MRI would not have been covered completely by the planning target volume (PTV) of the CT-only contour. Yet, median Hausdorff und DSI values did not reflect these differences. The 3-year local control rate was 94%.
conclusionsAdding a diagnostic MRI in RT treatment position is feasible and results in relevant changes in target volumes in the majority of patients.
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