ArticleBMC surgery2023
Incidental parathyroidectomy during total thyroidectomy and functional parathyroid preservation: a retrospective cohort study.
Article in BMC surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Incidental parathyroidectomy risk in thyroid carcinoma patients undergoing thyroidectomy: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2026Pooled it
- Trial
- Pathological characteristics rather than thyroid size predict incidental parathyroidectomy during thyroid surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Review
- Evolution of parathyroid pathology identification during concomitant thyroid surgery.Gland surgery · 2026Article
- Artificial intelligence for predicting transient hypocalcemia after total thyroidectomy.Scientific reports · 2026Article
- Impact of the COVID-19 Pandemic on parathyroid adenoma surgery: a single-center comparative experience.BMC surgery · 2026Article
- Risk stratification of incidental parathyroidectomy in patients undergoing thyroidectomy for nodular goiter: a retrospective cohort study.BMC surgery · 2025Article
- Preservation of parathyroid vascularization in thyroid surgery: morphological study and surgical implications.Surgical and radiologic anatomy : SRA · 2025Article
- Clinical significance and risk factors of incidental parathyroidectomy after total thyroidectomy.Endocrine · 2025Article
- One- or Two-Step Total Thyroidectomy for Cancer Indications: A 20-Year Retrospective Study from a Referral Center.Annals of surgical oncology · 2025Article
- Will the autofluorescence take over inadvertent parathyroidectomy? Results from a multicentre cohort study.Updates in surgery · 2025Article
- Propensity score-matched analysis of the '2+2' parathyroid strategy in total thyroidectomy with central neck dissection.Frontiers in endocrinology · 2025Article
- Incidental parathyroidectomy after thyroid surgery and relationship with postoperative hypocalcemia: a single tertiary center analysis.Updates in surgery · 2024Article
- Risk Factors for Transient Hypoparathyroidism after Total Thyroidectomy: Insights from a Cohort Analysis.Journal of clinical medicine · 2024Article
- Predictors of permanent hypoparathyroidism following total thyroidectomy: a retrospective analysis.Annals of Saudi medicineArticle
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe published rate of incidental parathyroidectomy (IP) during thyroid surgery varies between 5.8% and 29%. The risk factors and clinical significance of postoperative transient hypocalcemia and permanent hypoparathyroidism are still debated. The aims of this study were to assess the clinical relevance of avoidable IP for transient hypocalcemia and permanent hypoparathyroidism, and to describe the risk factors for IP.
methodsThis retrospective cohort study included 1,537 patients who had a one-step total thyroidectomy in a high-volume endocrine surgery center between 2018 and 2019. Pathology reports were reviewed for incidentally removed parathyroid glands. Intrathyroidal parathyroid glands were excluded from the study. Demographic characteristics, potential risk factors, and postoperative calcium and PTH levels were compared between IP and control groups.
resultsAvoidable IP occurred in 234 (15.2%) patients. Patients with IP had a higher risk of transient hypocalcemia (17.9% vs. 11.5%, p = 0.006; odds ratio [OR] 1.68, 95% confidence interval [95% CI]1.16-2.45) and permanent hypoparathyroidism (4.7% vs. 1.6%, p = 0.002; OR 3.01, 95% CI 1.29-6.63) than patients without IP. Multivariate analysis showed that central lymph node dissection (CLND) and incidental removal of thymus tissue were independent risk factors for IP (OR 4.83, 95% CI 2.71-8.86, p < 0.001 and OR 1.72, 95% CI 1.02-2.82, p = 0.038).
conclusionsPatients with IP were more likely to develop transient hypocalcemia and permanent hypoparathyroidism, indicating the clinical significance of avoidable IP for patients and the need for raising awareness among surgeons. Patients undergoing CLND are at a higher risk for IP, and should be adequately informed and treated. Any removal of thymus tissue should be avoided during CLND.
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