Evidence map›Paper›PMID 37674074›Full record

ArticleNature2023

Hydrogen-bond-acceptor ligands enable distal C(sp

Daniel A Strassfeld, Chia-Yu Chen, Han Seul Park, D Quang Phan, Jin-Quan Yu

Abstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Alcohol-Directed Carboamination of Conjugated Enynes.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Electrical Manipulation of Magnetic Domain Structure in van der Waals Ferromagnetic FeAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. BiVOChemical science · 2025
    Article
  8. From Mono-Accounts of chemical research · 2025
    Review
  9. Transition-Metal-Catalyzed C(spTopics in current chemistry (Cham) · 2025
    Review
  10. Article
  11. Palladium-Catalyzed Methylene β-C-H Fluorination of Native Amides.Journal of the American Chemical Society · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel A Strassfeld *Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3598-0793
Chia-Yu Chen *Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-1324-1394
Han Seul ParkDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
D Quang PhanDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0009-0006-1451-0601
Jin-Quan YuDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. yu200@scripps.edu.ORCID http://orcid.org/0000-0003-3560-5774

Funding

Ligand-promoted Enantioselective C-H Activation ReactionsR01GM084019 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2008 to 2024
$9.5M
Catalyst-Controlled Site-Selective C-H Functionalizations of Arenes and HeteroarenesR01GM102265 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2012 to 2023
$4.6M
Pd-Catalyzed C(sp3)-H Functionalizations Directed by Free Alcohols and Boc-Protected AminesF32GM143921 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI STRASSFELD, DANIEL AARON · 2022 to 2023
$137k
NIGMS NIH HHS F32 GM143921NIGMS NIH HHS R01 GM084019NIGMS NIH HHS R01 GM102265
6 · The paper itself

Abstract

The functionalization of C-H bonds in organic molecules is one of the most direct approaches for chemical synthesis. Recent advances in catalysis have allowed native chemical groups such as carboxylic acids, ketones and amines to control and direct C(sp

Identifiers

PMID37674074
PMCPMC11139439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.