Evidence map›Paper›PMID 37674061›Full record

ArticleZeitschrift fur Gerontologie und Geriatrie2024

Hypogonadism is frequent in very old men with multimorbidity and is associated with anemia and sarcopenia.

Sabine Schluessel, Martin Bidlingmaier, Sebastian Martini, Martin Reincke, Nicole Reisch, Anna Schaupp, Günter Stalla, Daniel Teupser, Ralf Schmidmaier, Michael Drey

Open access · hybridAbstract read
In one paragraph

Article in Zeitschrift fur Gerontologie und Geriatrie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Sabine SchluesselMedizinische Klinik und Poliklinik IV, Department of Geriatrics, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany. Sabine.Schluessel@med.uni-muenchen.de.
Martin BidlingmaierMedizinische Klinik und Poliklinik IV, Department of Endocrinology, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Sebastian MartiniMedizinische Klinik und Poliklinik IV, Department of Geriatrics, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Martin ReinckeMedizinische Klinik und Poliklinik IV, Department of Endocrinology, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Nicole ReischMedizinische Klinik und Poliklinik IV, Department of Endocrinology, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Anna SchauppMedizinische Klinik und Poliklinik IV, Department of Geriatrics, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Günter StallaMedicover Neuroendocrinology, Munich, Germany.
Daniel TeupserInstitute of Laboratory Medicine, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Ralf SchmidmaierMedizinische Klinik und Poliklinik IV, Department of Endocrinology, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
Michael DreyMedizinische Klinik und Poliklinik IV, Department of Geriatrics, LMU Klinikum, Ludwig-Maximilians-Universität München, Munich, Germany.
LMU Klinikum · DELudwig-Maximilians-Universität München · DEMedicover · DESabin Vaccine Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical data regarding hypogonadism in very old men with multimorbidity are rare. Hypogonadism can contribute to osteoporosis, anemia and sarcopenia and is therefore a relevant problem for geriatric patients.

methodsA total of 167 men aged 65-96 years (mean 81 ± 7 years) admitted to an acute geriatric ward were included in a cross-sectional study. Body composition derived from dual-energy X‑ray absorptiometry, bone mineral density, handgrip strength, multimorbidity, polypharmacy and laboratory values were obtained from the routine electronic clinical patient file.

resultsHypogonadism was present in 62% (n = 104) of the study participants, of whom 83% showed clinical manifestation of hypogonadism (hypogonadism in combination with anemia, sarcopenia and/or low T‑score). The subgroups showed a distribution of 52% primary and 48% secondary hypogonadism. Compared to the eugonadal patients, hypogonadal patients had reduced handgrip strength (p = 0.031) and lower hemoglobin levels (p = 0.043), even after adjustment for age, body mass index and glomerular filtration rate.

conclusionHypogonadism is common in geriatric patients. If chronic anemia, sarcopenia, or osteoporosis are diagnosed, testosterone levels should be determined in geriatric settings.

Indexed as

AnemiaHypogonadismOsteoporosisSarcopeniaAgedCross-Sectional StudiesHand StrengthHumansMaleMultimorbidityTestosteroneTestosteroneDual-energy X-ray absorptiometryGeriatricsOsteoporosisPrimary and secondary hypogonadismTestosterone

Identifiers

PMID37674061
PMCPMC10827893
OpenAlexW4386469181

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.