Evidence map›Paper›PMID 37674051›Full record

ReviewPediatric radiology2023

Recommendations for neuroradiological examinations in children living with achondroplasia: a European Society of Pediatric Radiology and European Society of Neuroradiology opinion paper.

Jenny Wright, Moira Cheung, Ata Siddiqui, Jonathan Lucas, Alistair Calder, Maria I Argyropoulou, Owen J Arthurs, Pablo Caro-Dominguez, Dominic Thompson, Mariasavina Severino and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guideline
  2. Foramen magnum decompression in infants and children with achondroplasia: clinical outcomes from a 15-patient surgical series.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Article
  4. [Achondroplasia : New era of orthopedic treatment?]Orthopadie (Heidelberg, Germany) · 2024
    Review
  5. Achondroplasia current concept of orthopaedic management.Journal of children's orthopaedics · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 4 countries.

Jenny WrightDepartment of Radiology, Manchester University NHS Foundation Trust, Oxford Road, Manchester, M13 9WL, UK. drjennywright@doctors.org.uk.ORCID http://orcid.org/0000-0002-6983-6530
Moira CheungDepartment of Paediatric Endocrinology, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, UK.ORCID http://orcid.org/0000-0003-0742-7595
Ata SiddiquiDepartment of Neuroradiology, Guy's and Saint Thomas' NHS Foundation Trust, London, UK.
Jonathan LucasPaediatric Spinal Surgery, Evelina London Children's Hospital, London, UK.
Alistair CalderDepartment of Radiology, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0001-8335-299X
Maria I ArgyropoulouDepartment of Clinical Radiology and Imaging, Medical School, University of Ioannina, Ioannina, Greece.ORCID http://orcid.org/0000-0001-7236-3706
Owen J ArthursDepartment of Radiology, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0003-1213-3516
Pablo Caro-DominguezUnidad de Radiologia Pediatrica, Servicio de Radiologia, Hospital Universitario Virgen del Rocio, Seville, Spain.ORCID http://orcid.org/0000-0003-3540-6580
Dominic ThompsonDepartment of Paediatric Neurosurgery, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, UK.
Mariasavina Severino *Neuroradiology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.ORCID http://orcid.org/0000-0003-4730-5322
Felice D'Arco *Department of Neuroradiology, Guy's and Saint Thomas' NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0001-7396-591X
members of the ESPR Neuroradiology Taskforce
members of the ESNR Pediatric Subcommittee
Great Ormond Street Hospital · GBEvelina London Children's Healthcare · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBHospital Universitario Virgen del Rocío · ESIstituto Giannina Gaslini · ITManchester University NHS Foundation Trust · GBUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children living with achondroplasia are at an increased risk of developing neurological complications, which may be associated with acute and life-altering events. To remediate this risk, the timely acquisition of effective neuroimaging that can help to guide clinical management is essential. We propose imaging protocols and follow-up strategies for evaluating the neuroanatomy of these children and to effectively identify potential neurological complications, including compression at the cervicomedullary junction secondary to foramen magnum stenosis, spinal deformity and spinal canal stenosis. When compiling these recommendations, emphasis has been placed on reducing scan times and avoiding unnecessary radiation exposure. Standardized imaging protocols are important to ensure that clinically useful neuroimaging is performed in children living with achondroplasia and to ensure reproducibility in future clinical trials. The members of the European Society of Pediatric Radiology (ESPR) Neuroradiology Taskforce and European Society of Neuroradiology pediatric subcommittee, together with clinicians and surgeons with specific expertise in achondroplasia, wrote this opinion paper. The research committee of the ESPR also endorsed the final draft. The rationale for these recommendations is based on currently available literature, supplemented by best practice opinion from radiologists and clinicians with subject-specific expertise.

Indexed as

AchondroplasiaRadiologyChildConstriction, PathologicForamen MagnumHumansInfantReproducibility of ResultsAchondroplasiaComputed tomographyCraniovertebral junctionForamen magnum stenosisMagnetic resonance imagingSpinal stenosis

Identifiers

PMID37674051
OpenAlexW4386469285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.