Evidence map›Paper›PMID 37673890›Full record

ReviewNPJ vaccines2023

Ensuring equity with pre-clinical planning for chlamydia vaccines.

Amanda L Collar, Tegan N Clarke, Andzoa N Jamus, Kathryn M Frietze

Open access · goldAbstract readReview
In one paragraph

Review in NPJ vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Profile ofHuman vaccines & immunotherapeutics · 2025
    Article
  3. Appraisal of the causal effect ofmedRxiv : the preprint server for health sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amanda L CollarDepartment of Molecular Genetics and Microbiology, School of Medicine, University of New Mexico, Albuquerque, NM, USA.ORCID http://orcid.org/0000-0003-3214-1898
Tegan N ClarkeDepartment of Molecular Genetics and Microbiology, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Andzoa N JamusDepartment of Molecular Genetics and Microbiology, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Kathryn M FrietzeDepartment of Molecular Genetics and Microbiology, School of Medicine, University of New Mexico, Albuquerque, NM, USA. kfrietze@salud.unm.edu.ORCID http://orcid.org/0000-0002-1428-8899
University of New Mexico · US

Funding

Biology of Infectious Diseases &InflammationT32AI007538 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Michelle A Ozbun · 1998 to 2026
$5.2M
Bacteriophage virus-like particle vaccines for Chlamydia trachomatis urogenital infectionR01AI166360 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Kathryn M. Frietze · 2023 to 2026
$1.5M
Bacteriophage virus-like particle vaccines against dengue virus non-structural protein 1R21AI148836 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI FRIETZE, KATHRYN M. · 2020 to 2021
$417k
Defining Chlamydia trachomatis adhesion factor epitope-specific antibody responses, functionality, and roles in protection against urogenital infectionF30AI156995 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI COLLAR, AMANDA L · 2021 to 2023
$120k
Investigation of novel chlamydia vaccines in male infection models and sexual transmission challengesF31AI179064 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI JAMUS, ANDZOA · 2023 to 2024
$75k
NIAID NIH HHS F30 AI156995NIAID NIH HHS F31 AI179064NIAID NIH HHS R01 AI166360NIAID NIH HHS R21 AI148836NIAID NIH HHS T32 AI007538
6 · The paper itself

Abstract

Chlamydia trachomatis (Ct) remains the most common bacterial sexually transmitted pathogen worldwide, causing significant morbidity particularly among women, including pelvic inflammatory disease, ectopic pregnancy, and infertility. Several vaccines are advancing through pre-clinical and clinical development, and it is likely that one or more vaccines will progress into human efficacy trials soon. In this Perspective, we present a case for considering the challenges of Ct vaccine development through a lens of equity and justice. These challenges include the need to protect against multiple serovars, in both females and males, at multiple anatomic sites, and in resource poor areas of the world. We propose that early consideration of vaccine implementation by conducting community-engaged research will ensure that a scientifically sound chlamydia vaccine promotes equity, justice, and shared-gendered responsibility for STI prevention.

Identifiers

PMID37673890
PMCPMC10482967
OpenAlexW4386481958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.