Evidence map›Paper›PMID 37673683›Full record

ArticleInternational journal of spine surgery2023

A Novel Multimodal Postoperative Pain Protocol for 1- to 2-Level Open Lumbar Fusions: A Retrospective Cohort Study.

Michael Markowitz, Barrett Woods, Gregory Schroeder, Christopher Kepler, David Kaye, Mark Kurd, Joshua Armstrong, Alexander Vaccaro, Kris Radcliff

Open access · diamondAbstract read
In one paragraph

Article in International journal of spine surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Michael MarkowitzRowan University School of Osteopathic Medicine Orthopedic Surgery, Stratford, NJ, USA.
Barrett WoodsThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Gregory SchroederThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Christopher KeplerThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
David KayeThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Mark KurdThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Joshua ArmstrongThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Alexander VaccaroThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Kris RadcliffThe Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA kris.radcliff@rothmanortho.com.
Rothman Institute · USThomas Jefferson University Hospital · USRowan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been increased interest in exploring methods to reduce postoperative pain without opioid medications. In 2015, a multimodal analgesia protocol was used involving the perioperative use of celecoxib, gabapentin, intravenous acetaminophen, lidocaine, and liposomal bupivacaine. Overall, the goal was to reduce the utilization of scheduled opioids in favor of nonopioid pain management.

methodsThe results of a consecutive series of 1- to 2-level open primary lumbar fusions were compared to a cohort of patients after the implementation the perioperative multimodal pain management protocol. Primary endpoints included patient-reported pain scores and secondary endpoints included length of stay.

resultsThere were 87 patients in the preprotocol cohort and 184 in the protocol cohort. Comparing protocol and preprotocol patients, there were no significant differences in patient demographics. There was significantly average lower pain in the protocol group on postoperative day (POD) 1 (4.50 vs 5.00,

conclusionOur novel multimodal pain management protocol significantly reduced postoperative pain, length of stay, and opioid consumption in this patient cohort. Opioid usage correlated to pain in the protocol patients, while the preprotocol patients had no correlation between opioid use and pain medication. CLINICAL RELEVANCE: In this study, we demonstrated that preoperative and intraoperative analgesia can reduce postoperative pain medication requirements. Furthermore, we introduced a novel concept of a correlation of pain with opioid consumption as a marker of effective pain management of breakthrough pain. LEVEL OF EVIDENCE: 4:

Indexed as

1- to 2-level lumbar fusionacetaminophengabapentinlidocainemorphinemultimodal analgesianarcoticopioidpain managementpostoperative painreduced opioid consumption after lumbar fusionspine fusion

Identifiers

PMID37673683
PMCPMC10753327
OpenAlexW4386470998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.