Evidence map›Paper›PMID 37673460›Full record

ArticleGenes & development2023

Putting a finger on histidine methylation.

Paul L Boutz

Open access · diamondAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes & development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Paul L BoutzDepartment of Biochemistry and Biophysics, Center for RNA Biology, Center for Biomedical Informatics, Wilmot Cancer Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York 14620, USA paul_boutz@urmc.rochester.edu.
University of Rochester · US

Funding

Genomics-based approaches to understanding mechanistic alterations of spliceosome function in disease statesR01GM141544 · NIGMS · UNIVERSITY OF ROCHESTER · PI BOUTZ, PAUL LAWRENCE · 2021 to 2025
$1.6M
NIGMS NIH HHS R01 GM141544
6 · The paper itself

Abstract

Specialized enzymes add methyl groups to the nitrogens of the amino acid histidine, altering the chemical properties of its imidazole ring and, in turn, the function of the modified (poly)peptide. In this issue of

Indexed as

Amino AcidsHistidineAnimalsMammalsMethylationMethyltransferasesOrganogenesisAmino AcidsHistidineMethyltransferasesCARNMT1degradationembryonic developmentembryonic lethalityhistidinemethylationmethyltransferasemRNAsplicingU2AF1zinc finger protein

Identifiers

PMID37673460
PMCPMC10546973
OpenAlexW4386475387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.