Evidence map›Paper›PMID 37673436›Full record

ArticleJournal of psychiatry & neuroscience : JPN

Common and disorder-specific cortical thickness alterations in internalizing, externalizing and thought disorders during early adolescence: an Adolescent Brain and Cognitive Development study.

Gechang Yu, Zhaowen Liu, Xinran Wu, Benjamin Becker, Kai Zhang, Huaxin Fan, Songjun Peng, Nanyu Kuang, Jujiao Kang, Guiying Dong and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of psychiatry & neuroscience : JPN. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 7 countries.

Gechang Yu *From the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Zhaowen Liu *From the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Xinran Wu *From the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Benjamin Becker *From the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Kai Zhang *From the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan) zhangjie80@fudan.edu.cn lena.palaniyappan@mcgill.ca.
Huaxin FanFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Songjun PengFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Nanyu KuangFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Jujiao KangFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Guiying DongFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Xing-Ming ZhaoFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Gunter SchumannFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Jianfeng FengFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Barbara J SahakianFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Trevor W RobbinsFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Lena PalaniyappanFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan) zhangjie80@fudan.edu.cn lena.palaniyappan@mcgill.ca.
Jie ZhangFrom the Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China (Yu, Wu, Fan, Peng, Kuang, Kang, Dong, Zhao, Feng, Sahakian, Robbins, Zhang); the Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence, Fudan University, Ministry of Education, China (Yu, Wu, Fan, Peng, Kuang, Feng, Zhang); the Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Mass., USA (Liu); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA (Liu); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass., USA (Liu); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China (Becker); the School of Computer Science and Technology, East China Normal University, Shanghai, China (Zhang); the Shanghai Center for Mathematical Sciences, Fudan University, Shanghai, China (Kang); the MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China (Dong, Zhao); the Zhangjiang Fudan International Innovation Center, Shanghai, China (Zhao); the PONS Centre Shanghai, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China (Schumann); the PONS Centre Berlin, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany (Feng); the Shanghai Center for Mathematical Sciences, Shanghai, China (Feng); the Department of Computer Science, University of Warwick, Coventry, UK (Feng); the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China (Feng); the Fudan ISTBI-ZJNU Algorithm Centre for Brain-inspired Intelligence, Zhejiang Normal University, Jinhua, China (Feng); the Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK (Sahakian); the Department of Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Robbins); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que., Canada (Palaniyappan); the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan); the Robarts Research Institute, Western University, London, Ont., Canada (Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Palaniyappan).
Douglas Mental Health University Institute · CAShanghai Center for Brain Science and Brain-Inspired Technology · CNMcGill University · CACambridge School · PTFudan University · CNMinistry of Education · MEShanghai Innovative Research Center of Traditional Chinese Medicine · CNUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA growing body of neuroimaging studies has reported common neural abnormalities among mental disorders in adults. However, it is unclear whether the distinct disorder-specific mechanisms operate during adolescence despite the overlap among disorders.

methodsWe studied a large cohort of more than 11 000 preadolescent (age 9-10 yr) children from the Adolescent Brain and Cognitive Development cohort. We adopted a regrouping approach to compare cortical thickness (CT) alterations and longitudinal changes between healthy controls (

resultsYouth with externalizing or internalizing disorders exhibited increased regional CT compared with controls. Externalizing ( LIMITATIONS: The sample size of the GWAS was relatively small.

conclusionOur study provides strong evidence for the presence of specificity in CT, developmental trajectories and underlying genetic underpinnings among externalizing and internalizing disorders during early adolescence. Our results support the neurobiological validity of the regrouping approach that could supplement the use of a dimensional approach in future clinical practice.

Indexed as

Genome-Wide Association StudyMental DisordersBrainCognitionHumansNeurobiology

Identifiers

PMID37673436
PMCPMC10495167
OpenAlexW4386476949

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