SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2023
Effects of continuous positive airway pressure therapy on glucose metabolism in patients with obstructive sleep apnoea and type 2 diabetes: a systematic review and meta-analysis.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Effects of continuous positive airway pressure therapy duration on patients with obstructive sleep apnoea and type 2 diabetes mellitus: a systematic review and meta-analysis.BMJ open respiratory research · 2026Pooled it
- The association between prediabetes and obstructive sleep apnea syndrome: a meta-analysis.Frontiers in endocrinology · 2026Pooled it
- The effect of non-pharmacological sleep interventions on glycaemic measures in adults with sleep disturbances and behaviours: A systematic review and meta-analysis.Diabetes & vascular disease researchPooled it
- Glycemic trends following hypoglossal nerve stimulation in patients with obstructive sleep apnea and type 2 diabetes.Sleep & breathing = Schlaf & Atmung · 2026Article
- Physiological phenotypes of obstructive sleep apnea identified by cluster analysis: Association with type 2 diabetes.Journal of diabetes investigation · 2026Article
- Adherence to CPAP in Randomized Controlled Trials in Obstructive Sleep Apnoea-A Meta-Analysis and Investigation of Predictors.Journal of clinical medicine · 2026Review
- Sleep apnoea and its consequences: from animal models to precision medicine.Sleep medicine · 2026Review
- GLP-1 Receptor Agonists at the Crossroads of Circadian Biology, Sleep, and Metabolic Disease.International journal of molecular sciences · 2026Review
- Comparative Diagnostic Performance of Serum α-Klotho and FGF-23 in Predicting Obstructive Sleep Apnea Severity: A Novel Biomarker Approach.Journal of clinical medicine · 2026Article
- Article
- Development and Validation of Prediction Models for Severe Obstructive Sleep Apnea Based on Periodic Health Examinations.The clinical respiratory journal · 2026Article
- Obstructive sleep apnea and mortality among older US adults with diabetes mellitus (1999-2019): a CDC WONDER longitudinal study.Annals of medicine and surgery (2012) · 2026Review
- 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Article
- The Relationship Between PSQI Scores and Glucose Metabolic Dysfunction in Patients with Newly Diagnosed T2DM: The Mediating Role of Body Composition.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Advancing sleep health equity through deep learning on large-scale nocturnal respiratory signals.Nature communications · 2025Article
- Determinants and rate of long-term adherence to continuous positive -airway pressure in obstructive sleep apnea: a multicenter retrospective study.Multidisciplinary respiratory medicine · 2025Article
- Impact of sleep apnea treatment on cardiometabolic parameters in a large national multicenter alliance registry.American journal of preventive cardiology · 2025Article
- Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine.American journal of lifestyle medicine · 2025Article
- On the imperative of including 24-h and longitudinal multidimensional physiological phenotyping in rodent models of sleep apnea.Sleep medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnoea is a highly prevalent chronic disorder and has been shown to be associated with disturbed glucose metabolism and type 2 diabetes. However, the evidence from individual clinical trials on the effect of continuous positive airway pressure (CPAP) treatment on glycaemic control in patients with co-existing obstructive sleep apnoea and type 2 diabetes remains controversial. A systematic review of randomised controlled trials assessing the effect of CPAP on glycaemic control in patients with obstructive sleep apnoea and type 2 diabetes was conducted using the databases MEDLINE, Embase, Cochrane and Scopus up to December 2022. Meta-analysis using a random-effect model was performed for outcomes that were reported in at least two randomised controlled trials. From 3031 records screened, 11 RCTs with a total of 964 patients were included for analysis. CPAP treatment led to a significant reduction in haemoglobin A1c (HbA1c) (mean difference -0.24%, 95% CI -0.43- -0.06%, p=0.001) compared to inactive control groups. Meta-regression showed a significant association between reduction in HbA1c and hours of nightly CPAP usage. CPAP therapy seems to significantly improve HbA1c and thus long-term glycaemic control in patients with type 2 diabetes and obstructive sleep apnoea. The amount of improvement is dependent on the hours of usage of CPAP and thus optimal adherence to CPAP should be a primary goal in these patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.