Evidence map›Paper›PMID 37673304›Full record

ArticleRespiratory physiology & neurobiology2023

Elevated risk of dyspnea in adults with obesity.

Josh T Goh, Bryce N Balmain, Daniel P Wilhite, Jorge Granados, Lydia L Sandy, Yu-Lun Liu, James A Pawelczyk, Tony G Babb

Open access · greenAbstract read
In one paragraph

Article in Respiratory physiology & neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
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  3. Comparative analysis ofFrontiers in physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Josh T GohInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center, Dallas, TX, USA.
Bryce N BalmainInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center, Dallas, TX, USA.
Daniel P WilhiteInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center, Dallas, TX, USA.
Jorge GranadosInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center, Dallas, TX, USA.
Lydia L SandyDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yu-Lun LiuPeter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA.
James A PawelczykNoll Laboratory, Department of Kinesiology, Pennsylvania State University, University Park, PA, USA.
Tony G BabbInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: DrTonyBabb@TexasHealth.org.
Southwestern Medical Center · USTexas Health Dallas · USThe University of Texas Southwestern Medical Center · USInstitute for Exercise and Environmental Medicine · USPennsylvania State University · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JOEL K. ELMQUIST · 2022 to 2026
$7.4M
Effects of Obesity in the AgedR01AG070262 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI BABB, TONY G · 2021 to 2024
$2.1M
Targeting breathing limitations to improve functional outcomes in HFpEFK99HL164957 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BALMAIN, BRYCE · 2023 to 2024
$270k
NCATS NIH HHS UL1 TR002014NHLBI NIH HHS K99 HL164957NIA NIH HHS R01 AG070262NIDDK NIH HHS P30 DK127984
6 · The paper itself

Abstract

We investigated whether older adults (OA) with obesity are more likely to have dyspnea compared with OA without obesity, and whether OA with obesity are at a greater risk of having dyspnea compared with middle-aged (MA) and younger adults (YA) with obesity. We obtained de-identified data from the TriNetX UT Southwestern Medical Center database. We identified obesity and dyspnea using ICD-10-CM codes E66 and R06.0, respectively. Patients were separated into three age groups: OA, (65-75 y.o.), MA (45-55 y.o.), and YA (25-35 y.o). Within these groups, those with and without obesity or dyspnea were identified for analysis. The risk of dyspnea was greater in OA (risk ratio: 3.64), MA (risk ratio: 3.52), and YA (risk ratio: 2.76) with obesity compared with age-matched patients without obesity (all p < 0.01). The risk of dyspnea was greater in OA and MA with obesity compared with YA with obesity (both p < 0.001 vs. YA). These findings suggest that clinicians should consider obesity as an independent risk factor for dyspnea.

Indexed as

DyspneaObesityAdultAgedAge FactorsFemaleHumansMaleMiddle AgedRisk FactorsAgingBreathlessnessObesityOverweight

Identifiers

PMID37673304
PMCPMC11087888
OpenAlexW4386474574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.