Evidence map›Paper›PMID 37672999›Full record

ArticleBiomaterials2023

Crossover of surface waves and capillary-viscous-elastic transition in soft biomaterials detected by resonant acoustic rheometry.

Eric C Hobson, Weiping Li, Nicole E Friend, Andrew J Putnam, Jan P Stegemann, Cheri X Deng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eric C HobsonDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 40109, USA.
Weiping LiDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 40109, USA.
Nicole E FriendDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 40109, USA.
Andrew J PutnamDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 40109, USA.
Jan P StegemannDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 40109, USA. Electronic address: jpstegmann@umich.edu.
Cheri X DengDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 40109, USA. Electronic address: cxdeng@umich.edu.
University of Michigan · US

Funding

Microscale Mechanobiology for Musculoskeletal Tissue Engineering using Advanced Ultrasound TechniquesR01DE026630 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DENG, CHERI X, STEGEMANN, JAN P. · 2017 to 2021
$1.8M
Bone Regeneration Using Osteogenic and Vasculogenic Tissue ModulesR01AR062636 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEGEMANN, JAN P. · 2014 to 2018
$1.7M
NIAMS NIH HHS R01 AR062636NIDCR NIH HHS R01 DE026630
6 · The paper itself

Abstract

Viscoelastic properties of hydrogels are important for their application in science and industry. However, rheological assessment of soft hydrogel biomaterials is challenging due to their complex, rapid, and often time-dependent behaviors. Resonant acoustic rheometry (RAR) is a newly developed technique capable of inducing and measuring resonant surface waves in samples in a non-contact fashion. By applying RAR at high temporal resolution during thrombin-induced fibrin gelation and ultraviolet-initiated polyethylene glycol (PEG) polymerization, we observed distinct changes in both frequency and amplitude of the resonant surface waves as the materials changed over time. RAR detected a series of capillary-elastic, capillary-viscous, and visco-elastic transitions that are uniquely manifested as crossover of different types of surface waves in the temporally evolving materials. These results reveal the dynamic interplay of surface tension, viscosity, and elasticity that is controlled by the kinetics of polymerization and crosslinking during hydrogel formation. RAR overcomes many limitations of conventional rheological approaches by offering a new way to comprehensively and longitudinally characterize soft materials during dynamic processes.

Indexed as

AcousticsBiocompatible MaterialsElasticityHydrogelsViscosityBiocompatible MaterialsHydrogelsHydrogelPhase transitionPolymerizationResonant acoustic rheometrySurface waveViscoelasticity

Identifiers

PMID37672999
PMCPMC13252593
OpenAlexW4386268617

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.