Evidence map›Paper›PMID 37672427›Full record

SynthesisJournal of applied oral science : revista FOB2023

Dental anomalies in individuals with osteogenesis imperfecta: a systematic review and meta-analysis of prevalence and comparative studies.

Heloisa Vieira Prado, Enio Cássio Barreto Soares, Natália Cristina Ruy Carneiro, Ivanete Cláudia de Oliveira Vilar, Lucas Guimarães Abreu, Ana Cristina Borges-Oliveira

Open access · diamondAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of applied oral science : revista FOB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heloisa Vieira PradoUniversidade Federal de Minas gerais, Faculdade de Odontologia, Departamento de Odontologia Social e Preventiva, Belo Horizonte, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0002-9061-5644
Enio Cássio Barreto SoaresUniversidade Federal de Minas gerais, Faculdade de Odontologia, Departamento de Odontologia Social e Preventiva, Belo Horizonte, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0003-0463-8469
Natália Cristina Ruy CarneiroUniversidade Federal de Minas gerais, Faculdade de Odontologia, Departamento de Odontopediatria, Belo Horizonte, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0002-3028-7095
Ivanete Cláudia de Oliveira VilarUniversidade Federal de Minas gerais, Faculdade de Odontologia, Departamento de Odontologia Social e Preventiva, Belo Horizonte, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0001-9106-4912
Lucas Guimarães AbreuUniversidade Federal de Minas gerais, Faculdade de Odontologia, Departamento de Odontopediatria, Belo Horizonte, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0003-2258-8071
Ana Cristina Borges-OliveiraUniversidade Federal de Minas gerais, Faculdade de Odontologia, Departamento de Odontologia Social e Preventiva, Belo Horizonte, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0003-3364-4024
Universidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteogenesis imperfecta (OI) is a rare genetic disorder primarily caused by mutations in the genes involved in the production of type 1 collagen. OI is also known as brittle bone disease.

objectiveThis study aims to describe the prevalence of dental anomalies (except dentinogenesis imperfecta) in individuals with OI, and compare the prevalence of dental anomalies between individuals with and without OI and between individuals with different types of OI. SEARCH

methodsSearches in PubMed, Web of Science, Scopus, Ovid, and gray literature were performed in October 2022. SELECTION CRITERIA: Observational studies (with or without a comparison group) that evaluated the prevalence of dental anomalies in individuals with OI. Data collection and analysis: Data items were extracted by two authors. Quality assessment employing the Joanna Briggs Institute checklists and meta-analyses was conducted. Results were provided in prevalence values and odds ratio (OR) / 95% confidence interval (CI). Strength of evidence was determined.

resultsEighteen studies were included. Most prevalent dental anomalies in individuals with OI included pulp obliteration (46.4%), dental impaction (33.5%), dental impaction of second molars (27%), and tooth agenesis (23.9%). Individuals with OI type III/IV had 20.16-fold greater chance of exhibiting tooth discoloration in comparison with individuals with OI type I (CI: 1.10-370.98). In comparison with the group without OI, the individuals with OI had 6.90-fold greater chance of exhibiting dental impaction (CI: 1.54-31.00). High methodological quality was found in 47% of the studies. Strength of evidence was low or very low.

conclusionsPulp obliteration, dental impaction, and tooth agenesis were the most prevalent dental anomalies in the OI group. Individuals with OI were more likely to have dental impaction than individuals without OI. Individuals with OI type III/IV (severe-moderate) are more likely to have tooth discoloration than individuals with OI type I (mild).

Indexed as

Osteogenesis ImperfectaTooth DiscolorationHumansPrevalence

Identifiers

PMID37672427
PMCPMC10506791
OpenAlexW4386431147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.