Evidence map›Paper›PMID 37672334›Full record

ArticleMicrobial genomics2023

IS

Yu Wan, Akshay Sabnis, Zaynab Mumin, Isabelle Potterill, Elita Jauneikaite, Colin S Brown, Matthew J Ellington, Andrew Edwards, Shiranee Sriskandan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Polymyxin heteroresistance inJournal of medical microbiology · 2026
    Article
  3. Article
  4. Experimental evolution ofMicrobiology spectrum · 2025
    Article
  5. Article
  6. Unlocking Nitrofurantoin: Understanding Molecular Mechanisms of Action and Resistance in Enterobacterales.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Review
  7. Improving nitrofurantoin resistance prediction inAntimicrobial agents and chemotherapy · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yu WanNIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
Akshay SabnisCentre for Bacterial Resistance Biology, Imperial College London, London, UK.
Zaynab MuminReference Services Division, National Infection Service, UK Health Security Agency, London, UK.
Isabelle PotterillReference Services Division, National Infection Service, UK Health Security Agency, London, UK.
Elita JauneikaiteNIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
Colin S BrownNIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
Matthew J EllingtonNIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
Andrew EdwardsCentre for Bacterial Resistance Biology, Imperial College London, London, UK.
Shiranee SriskandanNIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, UK.
UK Health Security Agency · GBImperial College London · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Nitrofurantoin is a broad-spectrum first-line antimicrobial used for managing uncomplicated urinary tract infection (UTI). Loss-of-function mutations in chromosomal genes

Indexed as

Escherichia coliNitrofurantoinMutationNitroreductasesOxygenNitrofurantoinNitroreductasesOxygencomparative genomicsEscherichia colihybrid genome assemblyinsertion sequencesIS1 elementsnitrofurantoin heteroresistancepopulation analysis profilingresistance mechanismstructural variationwhole-genome sequencing

Identifiers

PMID37672334
PMCPMC10569738
OpenAlexW4386466485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.