Evidence map›Paper›PMID 37672249›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2023

The proteasome regulates body weight and systemic nutrient metabolism during fasting.

Henning Tim Langer, Samuel R Taylor, Mujmmail Ahmed, Tiffany Perrier, Tanvir Ahmed, Marcus D Goncalves

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Henning Tim LangerDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States.
Samuel R TaylorDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States.
Mujmmail AhmedDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States.
Tiffany PerrierDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States.
Tanvir AhmedDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States.
Marcus D GoncalvesDepartment of Medicine, Weill Cornell Medicine, New York, New York, United States.ORCID 0000-0002-0784-9248
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ubiquitin-proteasome system (UPS) and the autophagy-lysosome pathway are the primary means of degradation in mammalian tissues. We sought to determine the individual contribution of the UPS and autophagy to tissue catabolism during fasting. Mice were overnight fasted for 15 h before regaining food access ("Fed" group,

Indexed as

Phosphatidylinositol 3-KinasesProteasome Endopeptidase ComplexAnimalsAutophagyBody WeightBortezomibFastingMammalsMiceNutrientsProteolysisProto-Oncogene Proteins c-aktUbiquitinWeight LossBortezomibNutrientsPhosphatidylinositol 3-KinasesProteasome Endopeptidase ComplexProto-Oncogene Proteins c-aktUbiquitinautophagyfastingglucoseproteasomeproteolysis

Identifiers

PMID37672249
PMCPMC10864006
OpenAlexW4386467593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.