Evidence map›Paper›PMID 37672151›Full record

ArticleDigestive diseases and sciences2023

Natural Course of Common Bile Duct Microlithiasis.

Yufang Cui, Jianglong Hong, Chen Shi, Cui Hu, Xiaochang Liu, Zhangwei Xu, Junjun Bao, Yang Li, Qiao Mei

Abstract read
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Article in Digestive diseases and sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

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3 · Its place in the literature

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0 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yufang CuiDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jianglong HongDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Chen ShiDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Cui HuDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiaochang LiuDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhangwei XuDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Junjun BaoDepartment of Endoscopy, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yang LiDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Qiao MeiDepartment of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei, China. meiqiaomq@aliyun.com.ORCID 0000-0002-0635-6564
Anhui Medical University · CN

Funding

SIRT3 regulates energy metabolism of cholangiocarcinoma cells by deacetylating HIF1A 2008085QH415
6 · The paper itself

Abstract

backgroundCommon bile duct microlithiasis (CBDM) with a diameter of ≤ 3 mm can pass spontaneously without causing any symptoms, but in some cases, it can also cause severe cholangitis and pancreatitis. The optimal strategy for managing CBDM is yet to be determined.

methodsData of 154 patients with CBDM were collected and divided into two groups: with endoscopic retrograde cholangiopancreatography (with ERCP, n = 82) and without ERCP (n = 72). Clinical outcomes, including the incidence of unfavorable outcomes (UOs), such as cholangitis and pancreatitis, were observed and compared between the two groups.

resultsThe incidence of UOs was significantly lower in the ERCP group than in the without ERCP group (3.7% vs. 23.6%, respectively, p < 0.001). Moreover, the total number of readmissions was also lower in the ERCP group than in the without ERCP group (p < 0.001). A multivariate analysis adjusted for age, sex, and the American Society of Anesthesiologists (ASA) class revealed that endoscopic sphincterotomy (EST) and cholecystectomy were associated with a lower risk of UOs.

conclusionThe high rate of UOs in CBDM patients without ERCP suggests that its natural clinical course may not be as favorable as previously suggested. This finding implies that efforts should be made to clear the bile ducts.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholedocholithiasisAdultAgedCholangitisCholecystectomyFemaleHumansMaleMiddle AgedPancreatitisRetrospective StudiesSphincterotomy, EndoscopicCommon bile duct microlithiasisEndoscopic retrograde cholangiopancreatographyNatural courseUnfavorable outcomes

Identifiers

PMID37672151
OpenAlexW4386466576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.