Evidence map›Paper›PMID 37671865›Full record

ArticleJournal of virology2023

Intertumoral heterogeneity impacts oncolytic vesicular stomatitis virus efficacy in mouse pancreatic cancer cells.

Dakota W Goad, Anna Y Nesmelova, Laurel R Yohe, Valery Z Grdzelishvili

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Development ofEmerging microbes & infections · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dakota W GoadDepartment of Biological Sciences, University of North Carolina at Charlotte , Charlotte, North Carolina, USA.
Anna Y NesmelovaDepartment of Biological Sciences, University of North Carolina at Charlotte , Charlotte, North Carolina, USA.
Laurel R YoheDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte , Charlotte, North Carolina, USA.
Valery Z GrdzelishviliDepartment of Biological Sciences, University of North Carolina at Charlotte , Charlotte, North Carolina, USA.ORCID 0000-0001-8715-3840
University of North Carolina at Charlotte · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4M
Rational Oncolytic Virotherapy For Pancreatic Cancer Using Vesicular Stomatitis VirusR15CA238864 · NCI · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI GRDZELISHVILI, VALERY ZURABOVICH · 2019 to 2019
$440k
NCI NIH HHS P30 CA077598NCI NIH HHS R15 CA238864
6 · The paper itself

Abstract

Oncolytic virus (OV) therapy is a promising virus-based approach against various malignancies, including pancreatic ductal adenocarcinoma (PDAC). Our previous studies demonstrated that human PDAC cell lines are highly variable in their permissiveness to OVs. Mouse PDAC cell lines, which are widely used for

Indexed as

Carcinoma, Pancreatic DuctalInterferon Type IOncolytic VirotherapyOncolytic VirusesPancreatic NeoplasmsAnimalsCell Line, TumorHumansMiceVesicular stomatitis Indiana virusInterferon Type Imouse model of pancreatic canceroncolytic therapypancreatic cancerpancreatic ductal adenocarcinomavesicular stomatitis virus

Identifiers

PMID37671865
PMCPMC10537684
OpenAlexW4386466477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.