Evidence map›Paper›PMID 37671705›Full record

ArticleLeukemia & lymphoma2023

Baseline correlates of frailty and its association with survival in United States veterans with acute myeloid leukemia.

Jennifer La, Michelle H Lee, Mary T Brophy, Nhan V Do, Jane A Driver, David P Tuck, Nathanael R Fillmore, Clark Dumontier

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia & lymphoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jennifer LaCSP Informatics Center, Massachusetts Veterans Epidemiology Research and Information Center, Boston, MA, USA.ORCID 0000-0003-2266-0221
Michelle H LeeDepartment of Internal Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0002-7847-4471
Mary T BrophyCSP Informatics Center, Massachusetts Veterans Epidemiology Research and Information Center, Boston, MA, USA.ORCID 0000-0003-2314-4368
Nhan V DoCSP Informatics Center, Massachusetts Veterans Epidemiology Research and Information Center, Boston, MA, USA.ORCID 0000-0001-6868-7011
Jane A DriverNew England Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, Boston, MA, USA.ORCID 0000-0001-9759-4607
David P TuckDepartment of Internal Medicine, Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0001-7313-5158
Nathanael R FillmoreCSP Informatics Center, Massachusetts Veterans Epidemiology Research and Information Center, Boston, MA, USA.ORCID 0000-0002-8058-3423
Clark DumontierNew England Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, Boston, MA, USA.ORCID 0000-0003-2582-7816
Boston University · USBrigham and Women's Hospital · USHarvard University · US

Funding

Integration of Geriatric Measures Alongside Disease-Based Measures to Advance Precision Oncology for Older Veterans with Multiple MyelomaIK2CX002218 · VA · VA BOSTON HEALTH CARE SYSTEM · PI DUMONTIER, CLARK WILLIAM · 2021 to 2024
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CSRD VA IK2 CX002218
6 · The paper itself

Abstract

Frailty is an important construct to measure in acute myeloid leukemia (AML). We used the Veterans Affairs Frailty Index (VA-FI) - calculated using readily available data within the VA's electronic health records - to measure frailty in U.S. veterans with AML. Of the 1166 newly diagnosed and treated veterans with AML between 2012 and 2022, 722 (62%) veterans with AML were classified as frail (VA-FI > 0.2). At a median follow-up of 252.5 days, moderate-severely frail veterans had significantly worse survival than mildly frail, and non-frail veterans (median survival 179 vs. 306 vs. 417 days,

Indexed as

FrailtyLeukemia, Myeloid, AcuteVeteransAgedElectronic Health RecordsFrail ElderlyGeriatric AssessmentHumansPrognosisUnited StatesAcute myeloid leukemiaelectronic frailty indexfrailtygeriatric oncologyoverall survivalveterans

Identifiers

PMID37671705
PMCPMC12087472
OpenAlexW4386467337

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.