Evidence map›Paper›PMID 37671461›Full record

ArticleJournal of the American Geriatrics Society2023

Antipsychotic use among older patients with dementia receiving home health care services: Prevalence, predictors, and outcomes.

Jinjiao Wang, Jenny Y Shen, Yeates Conwell, Fang Yu, Kobi Nathan, Kathi L Heffner, Yue Li, Thomas V Caprio

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Association Between State Essential Caregiver Programs and Antipsychotic Medication Use Rate in Nursing Homes During the COVID-19 Pandemic.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinjiao WangElaine Hubbard Center for Nursing Research on Aging, University of Rochester, School of Nursing, Rochester, New York, USA.ORCID 0000-0002-5629-8497
Jenny Y ShenDepartment of Medicine, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0003-0956-7209
Yeates ConwellDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0001-8517-2132
Fang YuEdson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.ORCID 0000-0002-9399-1987
Kobi NathanDivision of Geriatrics & Aging, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0003-4183-5568
Kathi L HeffnerElaine Hubbard Center for Nursing Research on Aging, University of Rochester, School of Nursing, Rochester, New York, USA.ORCID 0000-0003-1095-1873
Yue LiDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0001-7592-0299
Thomas V CaprioDivision of Geriatrics & Aging, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0002-7216-7358

Funding

U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
NIA NIH HHS 1R24AG064025NIA NIH HHS R24 AG064025
6 · The paper itself

Abstract

backgroundAntipsychotic use is a safety concern among older patients in home health care (HHC), particularly for those with Alzheimer's disease and related dementias (ADRD). The objective of this study was to examine the prevalence and predictors of antipsychotic use among older adults with and without ADRD who received HHC, and the association of antipsychotic use with outcomes among patients living with ADRD.

methodsIn this secondary analysis of adults ≥65 years receiving care from an HHC agency in New York in 2019 (N = 6684), we used data from the Outcome and Assessment Information Set, Medicare HHC claims, and home medication review results in the electronic HHC records during a 60-day HHC episode. ADRD was identified by diagnostic codes. Functional outcome was the change in the composite activities of daily living (ADL) score from HHC admission to HHC discharge (measured in 5833 patients), where a positive score means improvement and a negative score means decline. Data were analyzed using logistic (predictors) and linear regression (association with outcome) analyses.

resultsThe point prevalence of antipsychotic use was 17.2% and 6.6% among patients with and without ADRD, respectively. Among patients living with ADRD, predictors of antipsychotic use included having greater ADL limitations (odds ratio [OR] = 1.30, p = 0.01), taking more medications (OR = 1.04, p = 0.02), having behavioral and psychological symptoms (OR = 5.26, p = 0.002), and living alone (OR = 0.52, p = 0.06). Among patients living with ADRD, antipsychotic use was associated with having less ADL improvement at HHC discharge (β = -0.70, p < 0.001).

conclusionsHHC patients living with ADRD were more likely to use antipsychotics and to experience worse functional outcomes when using antipsychotics. Antipsychotics should be systematically reviewed and, if contraindicated or unnecessary, deprescribed. Efforts are needed to improve HHC patients' access to nonpharmacological interventions and to provide education for caregivers regarding behavioral approaches to manage symptoms in ADRD.

Indexed as

Alzheimer DiseaseAntipsychotic AgentsHome Care ServicesActivities of Daily LivingAgedHumansMedicarePrevalenceUnited StatesAntipsychotic AgentsAlzheimer's disease and related dementiasantipsychoticsdementia’ polypharmacyhome health care

Identifiers

PMID37671461
PMCPMC10841208

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.