Evidence map›Paper›PMID 37671352›Full record

ArticleRSC advances2023

A novel tetranuclear Cu(ii) complex for DNA-binding and

Shuhua Cao, Anlin Wang, Kaoxue Li, Zhiteng Lin, Hongwei Yang, Xiaolei Zhang, Jianmei Qiu, Xishi Tai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shuhua CaoCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.ORCID https://orcid.org/0000-0002-7343-522X
Anlin WangAffiliated Beijing Chaoyang Hospital, Capital Medical University No. 8 Gongren Tiyuchang Nanlu, Chaoyang District Beijing 100020 P. R. China.
Kaoxue LiCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.
Zhiteng LinCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.
Hongwei YangCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.
Xiaolei ZhangCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.
Jianmei QiuCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.
Xishi TaiCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China shuhua@wfu.edu.cn taixs@wfu.edu.cn.
Weifang University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel tetranuclear Cu(ii) complex (TNC) was successfully synthesized and characterized by X-ray single crystal diffraction. The interaction of the complex with calf thymus DNA (CT-DNA) has been studied by UV-vis absorption titration, fluorescence technology and molecular docking. The results indicated that TNC could bind to the DNA through an intercalative mode. The agarose gel electrophoresis experiment showed that TNC could cleave supercoiled plasmid DNA into linear DNA. The anticancer activity of TNC was tested on four cancer cell lines: MCF7, A549, 4T1 and HepG2. The results indicated that TNC shown significant activity against all of above cell lines.

Identifiers

PMID37671352
PMCPMC10476018
OpenAlexW4386412156

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.