Evidence map›Paper›PMID 37671278›Full record

ArticleFrontiers in veterinary science2023

Case report: Investigation of genetic mutations in a case of schistosomus reflexus in a Holstein dairy cattle fetus in Korea.

Woncheoul Park, Han-Ha Chai, Dajeong Lim, Changgwon Dang, Jaegu Lee, Jongho Kim, Hogyun Jeong, Taekwon Lee, Ki-Chang Lee, Kyunghyun Lee

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Woncheoul Park *Animal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration (RDA), Wanju-gun, Republic of Korea.
Han-Ha Chai *Animal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration (RDA), Wanju-gun, Republic of Korea.
Dajeong LimAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration (RDA), Wanju-gun, Republic of Korea.
Changgwon DangAnimal Genetics and Breeding Division, National Institute of Animal Science, Rural Development Administration (RDA), Cheonan-si, Chungcheongnam-do, Republic of Korea.
Jaegu LeeAnimal Genetics and Breeding Division, National Institute of Animal Science, Rural Development Administration (RDA), Cheonan-si, Chungcheongnam-do, Republic of Korea.
Jongho KimAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon-si, Republic of Korea.
Hogyun JeongVeterinary Medicine College, Jeongbuk National University, Iksan-si, Republic of Korea.
Taekwon LeeVeterinary Medicine College, Jeongbuk National University, Iksan-si, Republic of Korea.
Ki-Chang LeeVeterinary Medicine College, Jeongbuk National University, Iksan-si, Republic of Korea.
Kyunghyun LeeAnimal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon-si, Republic of Korea.
Animal and Plant Quarantine Agency · KRRural Development Administration · KRJeonbuk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schistosomus reflexus (SR) is one of the most common congenital anomalies found in cases of cattle dystocia; this disorder occurs mostly in cattle. Congenital anomalies such as SR are caused by various genetic and environmental factors, but no specific cause has been elucidated for SR. This study reports a case of SR in a Holstein dairy cattle fetus with congenital anomalies in Korea. Grossly, a distinct spine curvature was observed between the thoracic and lumbar vertebrae, accompanied by a consequential malformation from the sacrum to the occipital bone. Furthermore, the thoracic and abdominal organs were exposed. In computed tomography (CT) images, mild and severe kyphoscoliosis was observed in T1~11 and L1~6, respectively. Additionally, vertebral dysplasia was observed in S1~5 and Cd 1~5. To pinpoint the causal genes and mutations, we leveraged a custom 50K Hanwoo SNP-Chip and the Online Mendelian Inheritance in Animals (OMIA) database. As a result, we identified a nonsense mutation in apoptotic protease activating factor 1 (

Indexed as

fetusgenetic mutationHolsteinschistosomus reflexusSNP-Chipvertebrae dysplasia

Identifiers

PMID37671278
PMCPMC10475524
OpenAlexW4386027066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.