Evidence map›Paper›PMID 37671254›Full record

ReviewInternational journal of women's dermatology2023

Dermatologic care of patients with differences of sex development.

Sarah Gold, Christina Huang, Rakan Radi, Pranav Gupta, Eric I Felner, Jeehea Sonya Haw, Krista Childress, Nancy Sokkary, Vin Tangpricha, Michael Goodman and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of women's dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sarah GoldDepartment of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Christina HuangDepartment of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Rakan RadiDepartment of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Pranav GuptaDivision of Endocrinology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Eric I FelnerDivision of Endocrinology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Jeehea Sonya HawDivision of Endocrinology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Krista ChildressPediatric and Adolescent Gynecology, University of Utah, Primary Children's Hospital, Salt Lake City, Utah.
Nancy SokkaryPediatric and Adolescent Gynecology, Children's Healthcare of Atlanta, Atlanta, Georgia.
Vin TangprichaDivision of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Michael GoodmanDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia.
Howa YeungDepartment of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Federal Reserve · USEmory University · USChildren's Healthcare of Atlanta · US

Funding

Pathways to care and health outcomes among DSD patientsR01HD092595 · NICHD · EMORY UNIVERSITY · PI GOODMAN, MICHAEL, SANDBERG, DAVID ERIC · 2017 to 2021
$3.1M
Epidemiology, impact, and experience of acne in transgender personsK23AR075888 · NIAMS · EMORY UNIVERSITY · PI YEUNG, HOWA · 2020 to 2024
$789k
NIAMS NIH HHS K23 AR075888NIAMS NIH HHS L30 AR076081NICHD NIH HHS R01 HD092595
6 · The paper itself

Abstract

Background: Differences of sex development (DSD or disorders of sex development) are uncommon congenital conditions, characterized by atypical development of chromosomal, gonadal, or anatomic sex. Objective: Dermatologic care is an important component of the multidisciplinary care needed for individuals with DSD. This article discusses the most common primary dermatologic manifestations of DSD in addition to the cutaneous manifestations of hormonal and surgical therapies in individuals with DSD. Data sources: Published articles including case series and case reports on PubMed. Study selections: Selection was conducted by examining existing literature with a team of multidisciplinary specialists. Methods: Narrative review. Limitations: This article was not conducted as a systematic review. Results: In Klinefelter syndrome, refractory leg ulcers and incontinentia pigmenti have been described. Turner syndrome is associated with lymphatic malformations, halo nevi, dermatitis, and psoriasis. Virilization can be seen in some forms of congenital adrenal hyperplasia, where acne and hirsutism are common. Conclusion: Dermatologists should consider teratogenic risk for treatments of skin conditions in DSD depending on pregnancy potential. Testosterone replacement, commonly used for Klinefelter syndrome, androgen insensitivity syndrome, 5-alpha reductase deficiency, gonadal dysgenesis, or ovotesticular DSD, may cause acne.

Indexed as

acnecongenital adrenal hyperplasiadisorders of sex developmentintersexKlinefelter syndromeTurner syndrome

Identifiers

PMID37671254
PMCPMC10473340
OpenAlexW4386465787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.