Evidence map›Paper›PMID 37671176›Full record

ArticleOsteoarthritis and cartilage open2023

Prognostic value of illness perception on changes in knee pain among elderly individuals: Two-year results from the Frederiksberg Cohort study.

Elisabeth Ginnerup-Nielsen, Robin Christensen, Berit L Heitmann, Roy D Altman, Lyn March, Anthony Woolf, Henning Bliddal, Marius Henriksen

Registry-linked trialAbstract read
In one paragraph

Article in Osteoarthritis and cartilage open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03472300 (Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals From Frederiksberg Municipality - A Prospective Cohort Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03472300 active not recruitingnot on this map

Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals From Frederiksberg Municipality - A Prospective Cohort Study

TypeobservationalSponsorFrederiksberg University HospitalRan2018 to 2028Enrolled9,600ConditionsKnee Osteoarthritis, Survey, Family Life, Complementary Therapies, PainArmsSurvey about knee pain and treatment
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisabeth Ginnerup-NielsenThe Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Robin ChristensenThe Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Berit L HeitmannThe Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Roy D AltmanDivision of Rheumatology and Immunology, University of California, Los Angeles, CA 90095, USA.
Lyn MarchFlorance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital, and Kolling Institute; and Sydney Muskuloskeletal Health, University of Sydney, NSW Australia.
Anthony WoolfBone and Joint Research Group, Royal Cornwall Hospital, Truro TR1 3HD, UK.
Henning BliddalThe Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Marius HenriksenThe Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the prognostic value of illness perception (IP) on knee pain, quality of life (QoL) and functional level in elderly individuals reporting knee pain. Design: A prospective cohort study of 1552 elderly with knee pain comparing two previously established clusters based on the Brief Illness Perception questionnaire. Cluster 1 ("Concerned optimists" [hypothesized unfavorable profile]; n ​= ​642) perceived their knee pain as a greater threat to them than Cluster 2 ("Unconcerned confident" [hypothesized favorable profile]; n ​= ​910). Primary outcome was the change from baseline to year 2 in the KOOS Pain subscale. Secondary outcomes were changes from baseline in quality of life (EuroQol-5 Domain and EQ VAS) and in the KOOS subscales Symptom, Activities of Daily Living, Knee-related QoL and Sports and recreation. Analyses were done on the original Intention-To-Survey (ITS) population, using repeated measures mixed linear models. Results: Among the ITS population, 841 (54%) responded to the 2-year survey. There was a statistically significant but clinically irrelevant cluster difference in the 2-year change from baseline in KOOS pain (mean difference: 6.0 KOOS points [95% CI: 7.3 to -4.7]) explained by a minor improvement in Cluster 1: (6.2 points) and no changes in Cluster 2: (0.2 points). Comparable results were found across the secondary outcomes. Clinically irrelevant cluster changes in IP were seen. Conclusion: In a cohort of people with knee pain, IP phenotype (i.e., Clusters) were of no prognostic value for the 2-year changes in pain, function, and QoL. Targeting IP may not be relevant in this patient population. Trial registration number and date of registration: The Frederiksberg Cohort study was pre-registered at clinicaltrials.gov (NCT03472300) on March 21, 2018.

Indexed as

Cluster analysesCohort studyIllness perceptionKnee painPrognostic factorsQuality of life

Identifiers

PMID37671176
PMCPMC10475507

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.