Evidence map›Paper›PMID 37671159›Full record

ArticleFrontiers in immunology2023

Innate adaptive immune cell dynamics in tonsillar tissues during chronic SIV infection.

Rajni Kant Shukla, Manuja Gunasena, Nicole Reinhold-Larsson, Michael Duncan, Amila Hatharasinghe, Samuel Cray, Krishanthi Weragalaarachchi, Dhanuja Kasturiratna, Thorsten Demberg, Namal P M Liyanage

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Unveiling the immune dynamics ofInfection and immunity · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rajni Kant ShuklaDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Manuja GunasenaDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Nicole Reinhold-LarssonDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Michael DuncanDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Amila HatharasingheDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Samuel CrayDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Krishanthi WeragalaarachchiDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
Dhanuja KasturiratnaDepartment of Mathematics and Statistics, Northern Kentucky University, KY, Highland Heights, KY, United States.
Thorsten DembergDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, United States.
Namal P M LiyanageDepartment of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH, United States.
The Ohio State University · USBaylor College of Medicine · USNorthern Kentucky University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV-infected patients are at higher risk of developing oral mucosal infection and Epstein-Barr virus (EBV)-associated B cell malignancies. However, the potential role of oral immunity in the pathogenesis of oral lesions is unknown. Tonsils are oral-pharyngeal mucosal-associated lymphoid tissues that play an important role in oral mucosal immunity. In this study, we investigated the changes of innate and adaptive immune cells in macaque tonsils during chronic SIV infection. We found significantly higher frequencies of classical monocytes, CD3+CD56+ (NKT-like) cells, CD3

Indexed as

Epstein-Barr Virus InfectionsPersistent InfectionAnimalsHerpesvirus 4, HumanMouth MucosaPalatine TonsilCD161+T cellsmonocytesNKNKB cellsSIVT cellstonsils

Identifiers

PMID37671159
PMCPMC10475724
OpenAlexW4386032509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.