Evidence map›Paper›PMID 37671063›Full record

ArticleFrontiers in oncology2023

Cytological DNA methylation for cervical cancer screening: a validation set.

Linghua Kong, Linhai Wang, Ziyun Wang, Xiaoping Xiao, Yan You, Huanwen Wu, Ming Wu, Pei Liu, Lei Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Automated acquisition of explainable knowledge from unannotated colposcopic images for predicting the natural course of CIN2.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Advances in cervical cancer: current insights and future directions.Cancer communications (London, England) · 2025
    Review
  9. Review
  10. Article
  11. Assessment ofFrontiers in oncology · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Linghua KongDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Beijing, China.
Linhai WangDepartment of Technology, Beijing OriginPoly Biotechnology CO., Ltd., Beijing, China.
Ziyun WangDepartment of Technology, Beijing OriginPoly Biotechnology CO., Ltd., Beijing, China.
Xiaoping XiaoDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Beijing, China.
Yan YouDepartment of Pathology, Peking Union Medical College Hospital, Beijing, China.
Huanwen WuDepartment of Pathology, Peking Union Medical College Hospital, Beijing, China.
Ming WuDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Beijing, China.
Pei LiuDepartment of Technology, Beijing OriginPoly Biotechnology CO., Ltd., Beijing, China.
Lei LiDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNOriginWater (China) · CNPeking Union Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In a previous training set with a case-controlled design, cutoff values for host Methods: From June 1, 2019, to September 1, 2019, in our study center, we collected liquid-based samples from cervical swabs for methylation assays and hrHPV testing in eligible patients. The primary endpoint was the diagnostic accuracy of DNA methylation and hrHPV genotyping for CIN2+ according to confirmed histology results. Results: Among 307 participants, compared with hrHPV testing, the methylation assay for CIN2+ had lower sensitivity (68.7% versus 86.1%, Conclusions: The host

Indexed as

cervical cancercervical intraepithelial neoplasiaDNA methylationendometrial carcinomahigh-risk human papillomavirusvalidation set

Identifiers

PMID37671063
PMCPMC10475939
OpenAlexW4386032720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.