Evidence map›Paper›PMID 37670846›Full record

ArticleHealth science reports2023

Hospitalizations among children with sickle cell disease enrolled in the Kumasi Sickle Cell Pan African Consortium (SPARCo) database: A cross sectional study.

Yaa Gyamfua Oppong-Mensah, Samuel Frimpong Odoom, Isaac Nyanor, Evans Xorse Amuzu, Suraj Abubakar Yawnumah, Emmanuel Asafo-Adjei, Samuel Blay Nguah, Daniel Ansong, Alex Osei-Akoto, Vivian Paintsil

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yaa Gyamfua Oppong-MensahDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.ORCID 0000-0002-0808-7572
Samuel Frimpong OdoomDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.ORCID 0000-0001-8398-3898
Isaac NyanorDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Evans Xorse AmuzuDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.ORCID 0000-0001-5977-5706
Suraj Abubakar YawnumahDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Emmanuel Asafo-AdjeiDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Samuel Blay NguahDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Daniel AnsongDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Alex Osei-AkotoDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Vivian PaintsilDepartment of Child Health Komfo Anokye Teaching Hospital Kumasi Ghana.
Komfo Anokye Teaching Hospital · GH

Funding

The Sickle Pan-African Research Consortium (SPARCO)U24HL135881 · NHLBI · MUHIMBILI UNIVERSITY/ ALLIED HLTH SCIS · PI MAKANI, JULIE · 2017 to 2025
$5.3M
NHLBI NIH HHS U24 HL135881
6 · The paper itself

Abstract

Background and Aims: Sickle cell disease (SCD) is the commonest monogenic haemolytic disorder in Africa. Despite strides made in its management, a significant proportion of patients are hospitalized from the various complications of the disease. This study set out to describe the main causes and outcomes of hospitalizations among pediatric patients with SCD. Methods: A cross-sectional study was conducted at the Pediatric Emergency Unit of Komfo Anokye Teaching Hospital within a period of 12 months to recruit pediatric SCD patients. This study looked at causes of admission, length of hospital stay (LOS), and outcome of admission. Results: Of the 201 SCD patients recruited, 57.2% were males and majority were of SCD-SS phenotype 83.1%. The median age was 6 years. The three leading causes of hospitalization were Vaso-occlusive pain events (VOPE) (39.8%), acute chest syndrome (ACS) (25.9%), and infections (12.4%). Ten (5.0%) of the patients presented with a stroke. High admissions were observed in June (12.4%) and November (16.9%). The median (interquartile range [IQR]) LOS was 6 days (IQR: 4-10). Six (3.0%) of the patients died from complications of the disease during hospitalization. Conclusion: VOPE, ACS, infections, and acute anaemia from hyperhaemolysis were observed as the most common causes of admissions among SCD patients. A good outcome of discharge was seen in most of the patients that were hospitalized with a median length of stay of 6 days. This study also strengthens the importance of a good SCD database with patient follow-ups for better outcomes in SCD patients.

Indexed as

acute chest syndromehospitalizationinfectionslength of hospital staysickle cell diseaseVaso‐occlusive pain episodes

Identifiers

PMID37670846
PMCPMC10475768
OpenAlexW4386418506

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.